Corticosteroid-Induced Myopathy Questions & Answers

Updated: Jun 12, 2023
  • Author: Patrick M Foye, MD; Chief Editor: Stephen Kishner, MD, MHA  more...
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Questions & Answers

Overview

What is corticosteroid-induced myopathy?

What is the pathophysiology of corticosteroid-induced myopathy?

What is the incidence of corticosteroid-induced myopathy?

What is the mortality and morbidity of corticosteroid-induced myopathy?

How does the incidence of corticosteroid-induced myopathy vary by sex?

Presentation

Which history findings are characteristic of chronic (classic) corticosteroid-induced myopathy?

Which history findings are characteristic of acute (classic) corticosteroid-induced myopathy?

Which physical findings are characteristic of chronic corticosteroid-induced myopathy?

Which physical findings are characteristic of acute corticosteroid-induced myopathy?

DDX

Which conditions should be included in the differential diagnoses for corticosteroid-induced myopathy?

What are the differential diagnoses for Corticosteroid-Induced Myopathy?

Workup

What is the role of lab studies in the diagnosis of corticosteroid-induced myopathy?

What is the role of muscle biopsy in the diagnosis of chronic (classic) corticosteroid-induced myopathy?

What is the role of muscle biopsy in the diagnosis for acute corticosteroid-induced myopathy?

What are the findings of electromyography (EMG) and nerve conduction studies (NCSs) indicative of chronic (classic) corticosteroid-induced myopathy?

What are the findings of electromyography (EMG) and nerve conduction studies (NCSs) indicative of acute corticosteroid-induced myopathy, and how can ultrasonography be used in the diagnosis of myopathy?

Which histologic findings indicate corticosteroid-induced myopathy?

Treatment

What is the role of physical therapy in the treatment of corticosteroid-induced myopathy?

What is the role of occupational therapy in the treatment of corticosteroid-induced myopathy?

Which medical personnel provide consultations to patients affected with corticosteroid-induced myopathy?

How does decreasing steroid dosing affect corticosteroid-induced myopathy?

Which treatments are under investigation for corticosteroid-induced myopathy?

Medications

Which medications are used in the treatment of corticosteroid-induced myopathy?

Follow-up

How is corticosteroid-induced myopathy prevented?

What are complications of corticosteroid-induced myopathy?

What is the prognosis of corticosteroid-induced myopathy?

What is included in patient education about corticosteroid-induced myopathy?

How is corticosteroid-induced myopathy differentiated from polymyositis/dermatomyositis?