Physical Medicine and Rehabilitation for Charcot-Marie-Tooth Disease Questions & Answers

Updated: Feb 06, 2019
  • Author: Divakara Kedlaya, MBBS; Chief Editor: Elizabeth A Moberg-Wolff, MD  more...
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Questions & Answers

Overview

What is Charcot-Marie-Tooth disease (CMT)?

What is the pathophysiology of Charcot-Marie-Tooth disease (CMT)?

What is the prevalence of Charcot-Marie-Tooth disease (CMT) in the US?

What is the global prevalence of Charcot-Marie-Tooth disease (CMT)?

What is the morbidity associated with Charcot-Marie-Tooth disease (CMT)?

What are the racial predilections of Charcot-Marie-Tooth disease (CMT)?

What are the sex predilections of Charcot-Marie-Tooth disease (CMT)?

Which age group has the highest incidence of Charcot-Marie-Tooth disease (CMT) onset?

Presentation

Which clinical history findings are characteristic in Charcot-Marie-Tooth disease (CMT)?

Which physical findings are characteristic of Charcot-Marie-Tooth disease (CMT)?

What causes Charcot-Marie-Tooth disease (CMT)?

DDX

Which conditions are included in the differential diagnoses of Charcot-Marie-Tooth disease (CMT)?

What are the differential diagnoses for Physical Medicine and Rehabilitation for Charcot-Marie-Tooth Disease?

Workup

What is the role of lab tests in the workup of Charcot-Marie-Tooth disease (CMT)?

What is the role of imaging studies in the workup of Charcot-Marie-Tooth disease (CMT)?

What is the role of biopsy in the workup of Charcot-Marie-Tooth disease (CMT)?

What is the role of EMG/NCS in the workup of Charcot-Marie-Tooth disease (CMT)?

Which histologic findings are characteristic of Charcot-Marie-Tooth disease (CMT)?

Treatment

What is the role of physical therapy in the treatment of Charcot-Marie-Tooth disease (CMT)?

What is the role of occupational therapy in the treatment of Charcot-Marie-Tooth disease (CMT)?

What is the role of stem-cell and gene-transfer therapies in the treatment of Charcot-Marie-Tooth disease (CMT)?

What is the role of surgery in the treatment of Charcot-Marie-Tooth disease (CMT)?

Which specialist consultations are beneficial to patients with Charcot-Marie-Tooth disease (CMT)?

Medications

What is the role of medications in the treatment of Charcot-Marie-Tooth disease (CMT)?

Which medications in the drug class Anticonvulsants are used in the treatment of Physical Medicine and Rehabilitation for Charcot-Marie-Tooth Disease?

Which medications in the drug class Tricyclic Antidepressants are used in the treatment of Physical Medicine and Rehabilitation for Charcot-Marie-Tooth Disease?

Which medications in the drug class Analgesics are used in the treatment of Physical Medicine and Rehabilitation for Charcot-Marie-Tooth Disease?

Which medications in the drug class Cyclooxygenase-2 Inhibitors are used in the treatment of Physical Medicine and Rehabilitation for Charcot-Marie-Tooth Disease?

Which medications in the drug class Nonsteroidal Anti-inflammatory Drugs are used in the treatment of Physical Medicine and Rehabilitation for Charcot-Marie-Tooth Disease?

Follow-up

What is included in the long-term monitoring of Charcot-Marie-Tooth disease (CMT)?

How is Charcot-Marie-Tooth disease (CMT) prevented?

What are the possible complications of Charcot-Marie-Tooth disease (CMT)?

What is the prognosis of Charcot-Marie-Tooth disease (CMT)?

What is included in the patient education about Charcot-Marie-Tooth disease (CMT)?