Neoplastic Lumbosacral Plexopathy Follow-up

Updated: Aug 31, 2023
  • Author: Rajesh R Yadav, MD; Chief Editor: Dean H Hommer, MD  more...
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  • Neoplastic lumbosacral plexopathy (NLP) progresses much faster than does radiation-related plexopathy, and the patient survival rate is limited. Median survival is 5.5 months from the time of diagnosis, with a range of 1-34 months. In one study, at 1-month follow-up visit, only 15-17% of patients demonstrated improvement in pain or weakness, and 28% showed improvement in CT scan findings. Over half of the patients (59%) demonstrated gradual worsening of neurologic deficits.

  • In another study, 13 patients who underwent palliative irradiation for NLP had median survival of 185 days, with a range of 47-636 days. [29]