Physical Medicine and Rehabilitation for Complex Regional Pain Syndromes Differential Diagnoses

Updated: Feb 06, 2019
  • Author: Manish K Singh, MD; Chief Editor: Stephen Kishner, MD, MHA  more...
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Diagnostic Considerations

Erythromelalgia is a rare and poorly understood clinical syndrome characterized by hot, red, painful extremities. The condition commonly affects the lower extremities. The application of cold or elevation of the extremity may provide pain relief.

The syndrome is classified either as primary (idiopathic) erythromelalgia or as secondary erythromelalgia, which is commonly associated with myeloproliferative, syndrome-related thrombocythemia. Adults with erythromelalgia may get relief with a daily dose of aspirin.

Differential Diagnoses