Dupuytren Contracture Questions & Answers

Updated: Nov 20, 2018
  • Author: Eva Kovacs, MD; Chief Editor: Herbert S Diamond, MD  more...
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Questions & Answers

Overview

What is Dupuytren contracture?

What are the stages of Dupuytren contracture?

How is Dupuytren contracture graded?

What is the anatomy of the hand relevant to Dupuytren contracture?

How are the cardinal features of Dupuytren contracture characterized?

What is the role of immunologic factors in the etiology of Dupuytren contracture?

What is the pathophysiology of Dupuytren contracture?

What is the role of genetics in the etiology of Dupuytren contracture?

What are the risk factors for Dupuytren contracture?

What is the role of trauma in the etiology of Dupuytren contracture?

What is the role of diabetes mellitus in the etiology of Dupuytren contracture?

What is the role of smoking in the etiology of Dupuytren contracture?

What is the role of androgens in the etiology of Dupuytren contracture?

What is the role of epilepsy and antiepileptic medications in the etiology of Dupuytren contracture?

What is the role of barbiturate medications in the etiology of Dupuytren contracture?

What is the role of HIV infection in the etiology of Dupuytren contracture?

What is the prevalence of Dupuytren contracture?

What is the morbidity associated with Dupuytren contracture?

What are the racial predilections of Dupuytren contracture?

What are the sexual predilections of Dupuytren contracture?

Which age groups have the highest prevalence of Dupuytren contracture?

What is included in the patient education about Dupuytren contracture?

Presentation

What are the signs and symptoms of Dupuytren contracture?

Which conditions may be associated with Dupuytren contracture?

Which clinical history findings are characteristic of Dupuytren contracture?

Which physical findings are characteristic of Dupuytren contracture?

DDX

How is trigger finger differentiated from Dupuytren contracture?

How is stenosing tenosynovitis and ganglion cyst differentiated from Dupuytren contracture?

How is sarcoma differentiated from Dupuytren contracture in younger patients?

Which conditions are included in the differential diagnoses of Dupuytren contracture?

What are the differential diagnoses for Dupuytren Contracture?

Workup

How is Dupuytren contracture diagnosed?

Which histologic findings are characteristic of Dupuytren contracture?

What are the histologic stages of Dupuytren contracture?

Treatment

How is Dupuytren contracture treated?

When is observation indicated for the treatment for Dupuytren contracture?

What is the role of rehabilitation therapies in the treatment of Dupuytren contracture?

What is the role of corticosteroid injection in the treatment of Dupuytren contracture?

What is the role of tamoxifen in the treatment of Dupuytren contracture?

What is the role of anti-tumor necrosis factor (TNF) in the treatment of Dupuytren contracture?

What is the role of radiotherapy in the treatment of Dupuytren contracture?

What is the role of 5-Fluorouracil in the treatment of Dupuytren contracture?

What is the role of imiquimod in the treatment of Dupuytren contracture?

What is the role of botulinum toxin in the treatment of Dupuytren contracture?

What is the role of hyperbaric oxygen in the treatment of Dupuytren contracture?

What is the role of collagenase injection in the treatment of Dupuytren contracture?

What is the role of surgery in the treatment of Dupuytren contracture?

What is the efficacy of collagenase Clostridium histolyticum (CCH; Xiaflex) injection in the treatment of Dupuytren contracture?

Which specialist consultations are beneficial to patients with Dupuytren contracture?

What is the role of physical therapy in the treatment of Dupuytren contracture?

What is the role of occupational therapy in the treatment of Dupuytren contracture?

What is the role of percutaneous needle fasciotomy (PNF) in the treatment of Dupuytren contracture?

What are the contraindications to percutaneous needle fasciotomy (PNF) to treat Dupuytren contracture?

What is the role of open fasciotomy in the treatment of Dupuytren contracture?

What is the role of segmental aponeurotomy in the treatment of Dupuytren contracture?

What is a regional (selective) fasciectomy in the treatment of Dupuytren contracture?

What is an extensive (radical) fasciectomy in the treatment of Dupuytren contracture?

What is a dermofasciectomy in the treatment of Dupuytren contracture?

How is surgery selected for Dupuytren contracture?

How is surgery performed for the treatment of Dupuytren contracture?

What are the options for wound closure following surgery for Dupuytren contracture?

What is included in postoperative care following fasciectomy for the treatment of Dupuytren contracture?

Medications

What is the role of medications in the treatment of Dupuytren contracture?

Which medications in the drug class Corticosteroids are used in the treatment of Dupuytren Contracture?

Which medications in the drug class Enzymes are used in the treatment of Dupuytren Contracture?