Polymyalgia Rheumatica Differential Diagnoses

Updated: Nov 10, 2020
  • Author: Ehab R Saad, MD, MA, FACP, FASN; Chief Editor: Herbert S Diamond, MD  more...
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Diagnostic Considerations

Problems to be considered in the differential diagnosis of polymyalgia rheumatica include the following:

  • Acute or chronic infection

  • Infective endocarditis

  • Bursitis/tendinitis

  • Cervical spondylosis

  • Dermatomyositis

  • Malignancy

  • Myopathy

  • Parkinson disease

  • Remitting seronegative symmetrical synovitis with pitting edema (RS3PE)

  • Shoulder disorders (eg, shoulder synovitis, rotator cuff tendinitis, and subdeltoid bursitis)

  • Calcium pyrophosphate deposition disease

  • Late-onset ankylosing spondylitis

  • Vasculitis (eg, giant cell arteritis)

Differential Diagnoses