Scleroderma Differential Diagnoses

Updated: Dec 08, 2017
  • Author: Sergio A Jimenez, MD, MACR, FACP, FRCP(UK Hon); Chief Editor: Herbert S Diamond, MD  more...
  • Print
DDx

Diagnostic Considerations

The following disorders may present clinical similarities with systemic sclerosis (“scleroderma mimics”) and need to be included in the differential diagnosis: [96, 97, 98, 99]

Gadolinium-based contrast agents, bleomycin, pentazocine, and several other drugs and chemicals have been shown to cause disorders resembling systemic sclerosis. These must be considered in the differential diagnosis.