Antiphospholipid Syndrome Differential Diagnoses

Updated: Jul 22, 2022
  • Author: Suneel Movva, MD; Chief Editor: Herbert S Diamond, MD  more...
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Diagnostic Considerations

Other problems to be considered in the differential diagnosis include the following:

  • Hypercoagulable state: Malignancy, oral contraceptive use and hormone replacement therapy, homocystinemia, antithrombin III deficiency, protein C or S deficiency, factor V Leiden mutation, prothrombin A20210 mutation, antiprothrombin antibodies

  • Atherosclerotic vascular disease, including multiple cholesterol emboli syndrome

  • Systemic necrotizing vasculitis

Differential Diagnoses