Gonococcal Arthritis Questions & Answers

1. Dalla Vestra M, Rettore C, Sartore P, Velo E, Sasset L, Chiesa G, et al. Acute septic arthritis: remember gonorrhea. Rheumatol Int. 2008 Nov. 29(1):81-5. [QxMD MEDLINE Link].

2. Li R, Hatcher JD. Gonococcal Arthritis. 2023 Jan. 5 (2):211-23. [QxMD MEDLINE Link]. [Full Text].

3. Saini A, Eichenseer C, Meyers A, Frousiakis P. Septic gonococcal arthritis in a pediatric patient: Rare case report. Int J Surg Case Rep. 2021 Mar. 80:105701. [QxMD MEDLINE Link]. [Full Text].

4. Rice PA. Gonococcal arthritis (disseminated gonococcal infection). Infect Dis Clin North Am. 2005 Dec. 19(4):853-61. [QxMD MEDLINE Link].

5. Centers for Disease Control and Prevention. Sexually Transmitted Disease Surveillance 2021. Atlanta: U.S. Department of Health and Human Services; April 11, 2023. [Full Text].

6. Roth A, Mattheis C, Muenzner P, Unemo M, Hauck CR. Innate recognition by neutrophil granulocytes differs between Neisseria gonorrhoeae strains causing local or disseminating infections. Infect Immun. 2013 Jul. 81(7):2358-70. [QxMD MEDLINE Link].

7. World Health Organization. Sexually Transmitted Infections (STIs). Available at https://www.who.int/news-room/fact-sheets/detail/sexually-transmitted-infections-(stis). August 22, 2022; Accessed: May 25, 2023.

8. Belkacem A, Caumes E, Ouanich J, Jarlier V, Dellion S, Cazenave B, et al. Changing patterns of disseminated gonococcal infection in France: cross-sectional data 2009-2011. Sex Transm Infect. 2013 Dec. 89 (8):613-5. [QxMD MEDLINE Link].

9. Tuttle CS, Van Dantzig T, Brady S, Ward J, Maguire G. The epidemiology of gonococcal arthritis in an Indigenous Australian population. Sex Transm Infect. 2015 Mar 19. [QxMD MEDLINE Link].

10. Balsa A, Martin-Mola E. Infectious arthritis I: bacterial arthritis. Hochberg MC, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH. Rheumatology. 6th ed. Philadelphia, PA: Mosby Elsevier; 2015. 1013-28.

11. Beatrous SV, Grisoli SB, Riahi RR, Matherne RJ, Matherne RJ. Cutaneous manifestations of disseminated gonococcemia. Dermatol Online J. 2017 Jan 15. 23 (1):[QxMD MEDLINE Link].

12. Low SY, Ong CW, Hsueh PR, Tambyah PA, Yeo TT. Neisseria gonorrhoeae paravertebral abscess. J Neurosurg Spine. 2012 Jul. 17(1):93-7. [QxMD MEDLINE Link].

13. Klein N, Bürvenich L, Büchler C. Case report: Disseminated gonococcal infection, a story of camouflage and deceit. Eur J Microbiol Immunol (Bp). 2023 Apr 19. [QxMD MEDLINE Link].

14. Davis BT, Pasternack MS. Case records of the Massachusetts General Hospital. Case 19-2007 - a 19-year-old college student with fever and joint pain. N Engl J Med. 2007 Jun 21. 356(25):2631-7. [QxMD MEDLINE Link].

15. Carlin E, Urban C, Sidle J, Cirilli A, Larson J, Richman M, et al. Gonococcal Tenosynovitis Diagnosed with the Aid of Emergency Department Bedside Ultrasound. J Emerg Med. 2018 Jun. 54 (6):844-848. [QxMD MEDLINE Link].

16. Liebling MR, Arkfeld DG, Michelini GA, Nishio MJ, Eng BJ, Jin T, et al. Identification of Neisseria gonorrhoeae in synovial fluid using the polymerase chain reaction. Arthritis Rheum. 1994 May. 37(5):702-9. [QxMD MEDLINE Link].

17. Read P, Abbott R, Pantelidis P, Peters BS, White JA. Disseminated gonococcal infection in a homosexual man diagnosed by nucleic acid amplification testing from a skin lesion swab. Sex Transm Infect. 2008 Oct. 84(5):348-9. [QxMD MEDLINE Link].

18. Kimmitt PT, Kirby A, Perera N, Nicholson KG, Schober PC, Rajakumar K, et al. Identification of Neisseria gonorrhoeae as the causative agent in a case of culture-negative dermatitis-arthritis syndrome using real-time PCR. J Travel Med. 2008 Sep-Oct. 15(5):369-71. [QxMD MEDLINE Link].

19. Centers for Disease Control and Prevention. Update to CDC’s Sexually Transmitted Diseases Treatment Guidelines 2006: Fluoroquinolones no longer recommended for treatment of gonococcal infections. Available at http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5614a3.htm. April 13, 2007; Accessed: May 29, 2023.

20. Centers for Disease Control and Prevention (CDC). Update to CDC's Sexually Transmitted Diseases Treatment Guidelines, 2010: Oral Cephalosporins No Longer a Recommended Treatment for Gonococcal Infections. MMWR Morb Mortal Wkly Rep. 2012 Aug 10. 61:590-4. [QxMD MEDLINE Link].

21. [Guideline] Centers for Disease Control and Prevention. UPDATED GONORRHEA TREATMENT RECOMMENDATIONS. CDC.gov. Available at https://www.cdc.gov/std/tg2015/gonorrhea.htm. December 18, 2020; Accessed: April 21, 2021.

22. [Guideline] Workowski KA, Bachmann LH, Chan PA, Johnston CM, Muzny CA, Park I, et al. Sexually Transmitted Infections Treatment Guidelines, 2021. MMWR Recomm Rep. 2021 Jul 23. 70 (4):1-187. [QxMD MEDLINE Link]. [Full Text].

23. Kirkcaldy RD, Harvey A, Papp JR, Del Rio C, Soge OO, Holmes KK, et al. Neisseria gonorrhoeae Antimicrobial Susceptibility Surveillance - The Gonococcal Isolate Surveillance Project, 27 Sites, United States, 2014. MMWR Surveill Summ. 2016 Jul 15. 65 (7):1-19. [QxMD MEDLINE Link]. [Full Text].

Victoria Fernandes Sullivan, MD Chief of Medicine, William Beaumont Army Medical Center

Victoria Fernandes Sullivan, MD is a member of the following medical societies: American College of Physicians, American College of Rheumatology

Disclosure: Nothing to disclose.

Rachel Robbins, MD, FACP Assistant Professor of Medicine, Uniformed Services University of the Health Sciences; Staff Rheumatologist, Walter Reed National Military Medical Center

Rachel Robbins, MD, FACP is a member of the following medical societies: Alpha Omega Alpha, American College of Physicians, American College of Rheumatology, Association of Program Directors in Internal Medicine

Disclosure: Nothing to disclose.

Michael P Keith, MD, FACP, FACR Chief of Rheumatology, Walter Reed National Military Medical Center; Associate Professor of Medicine, Uniformed Services University of the Health Sciences, F Edward Hebert School of Medicine

Michael P Keith, MD, FACP, FACR is a member of the following medical societies: American College of Physicians, American College of Rheumatology, Clinical Immunology Society

Disclosure: Nothing to disclose.

Herbert S Diamond, MD Visiting Professor of Medicine, Division of Rheumatology, State University of New York Downstate Medical Center; Chairman Emeritus, Department of Internal Medicine, Western Pennsylvania Hospital

Herbert S Diamond, MD is a member of the following medical societies: Alpha Omega Alpha, American College of Physicians, American College of Rheumatology, American Medical Association, Phi Beta Kappa

Disclosure: Nothing to disclose.

Lawrence H Brent, MD Associate Professor of Medicine, Jefferson Medical College of Thomas Jefferson University; Chair, Program Director, Department of Medicine, Division of Rheumatology, Albert Einstein Medical Center

Lawrence H Brent, MD is a member of the following medical societies: American Association for the Advancement of Science, American Association of Immunologists, American College of Physicians, and American College of Rheumatology

Disclosure: Genentech Honoraria Speaking and teaching; Genentech Grant/research funds Other; Amgen Honoraria Speaking and teaching; Pfizer Honoraria Speaking and teaching; Abbott Immunology Honoraria Speaking and teaching; Takeda Honoraria Speaking and teaching; UCB Speaking and teaching; Omnicare Consulting fee Consulting; Centocor Consulting fee Consulting

Timothy M Straight, MD Instructor, Department of Medicine, Uniformed Services University School of Medicine

Timothy M Straight, MD is a member of the following medical societies: American College of Physicians

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

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