Leukocytoclastic Vasculitis Questions & Answers

Updated: Oct 25, 2018
  • Author: A Brooke W Eastham, MD; Chief Editor: Herbert S Diamond, MD  more...
  • Print
Questions & Answers

Overview

What is leukocytoclastic vasculitis (LCV)?

What is Henoch-Schönlein purpura (HSP)?

How frequently is leukocytoclastic vasculitis (LCV) idiopathic?

Where in the body does leukocytoclastic vasculitis (LCV) manifest?

What is the prognosis of leukocytoclastic vasculitis (LCV)?

What are the forms of leukocytoclastic vasculitis (LCV)?

What is the pathophysiology of leukocytoclastic vasculitis (LCV)?

What is the incidence of leukocytoclastic vasculitis (LCV) in the US?

What is the global incidence of leukocytoclastic vasculitis (LCV)?

What is the prognosis of leukocytoclastic vasculitis (LCV)?

What are the racial predilections of leukocytoclastic vasculitis (LCV)?

How does the prevalence of leukocytoclastic vasculitis (LCV) vary by sex?

How does the prevalence of leukocytoclastic vasculitis (LCV) vary by age?

Presentation

What are the signs and symptoms of leukocytoclastic vasculitis (LCV)?

Which disorders may be comorbid with leukocytoclastic vasculitis (LCV)?

What should be the focus of the medical history in suspected leukocytoclastic vasculitis (LCV)?

Why is consideration of the underlying disorder required in the evaluation of leukocytoclastic vasculitis (LCV)?

What is the most common manifestation of leukocytoclastic vasculitis (LCV)?

Which types of lesions may develop in patients with leukocytoclastic vasculitis (LCV)?

How is urticarial vasculitis differentiated from leukocytoclastic vasculitis (LCV) during the physical exam?

How is the duration of individual leukocytoclastic vasculitis (LCV) lesions determined?

How is hypocomplementemic urticarial vasculitis differentiated from leukocytoclastic vasculitis (LCV) during physical exam?

What should be included in the physical exam of suspected leukocytoclastic vasculitis (LCV)?

What are the causes of leukocytoclastic vasculitis (LCV)?

What are the most common drugs that cause leukocytoclastic vasculitis (LCV)?

Which infections may cause leukocytoclastic vasculitis (LCV)?

How often is can an infectious etiology be differentiated for a drug-related cause of leukocytoclastic vasculitis (LCV)?

What is the prevalence of a collagen-vascular disease etiology of leukocytoclastic vasculitis (LCV)?

What are the GI causes of leukocytoclastic vasculitis (LCV)?

What is the role of malignancy in the etiology of leukocytoclastic vasculitis (LCV)?

What are the signs and symptoms of a malignant etiology for leukocytoclastic vasculitis (LCV)?

Which larger-vessel vasculitis conditions are associated with leukocytoclastic vasculitis (LCV)?

DDX

Which conditions should be included in the differential diagnoses of leukocytoclastic vasculitis (LCV)?

What are the differential diagnoses for Leukocytoclastic Vasculitis?

Workup

What are the goals of evaluation of a patient with leukocytoclastic vasculitis (LCV)?

What is the role of lab testing in the evaluation of leukocytoclastic vasculitis (LCV)?

When are serologic studies indicated for the evaluation of leukocytoclastic vasculitis (LCV)?

When should complement levels be obtained in the evaluation of leukocytoclastic vasculitis (LCV)?

Which lab studies are indicated in the evaluation of leukocytoclastic vasculitis (LCV) without an identified etiology?

Which additional studies may be useful in the diagnosis of leukocytoclastic vasculitis (LCV)?

When is testing for malignancy indicated in the evaluation of leukocytoclastic vasculitis (LCV)?

What is the role of imaging studies in the evaluation of leukocytoclastic vasculitis (LCV)?

What are some other tests used for the diagnosis of hypocomplementemic urticarial vasculitis syndrome (HUVS)

What is the purpose of direct immunofluorescence (DIF) microscopy in the diagnosis of leukocytoclastic vasculitis (LCV)?

What is the role of skin biopsy in the evaluation of leukocytoclastic vasculitis (LCV)?

What is the role of muscle, nerve, or visceral organ biopsy in the evaluation of leukocytoclastic vasculitis (LCV)?

Which biopsy findings are characteristic of leukocytoclastic vasculitis (LCV)?

Which histologic findings are characteristic of leukocytoclastic vasculitis (LCV)?

What does immunofluorescent staining reveal in patients with leukocytoclastic vasculitis (LCV)?

Treatment

What are treatment options for leukocytoclastic vasculitis (LCV)?

How are the urticarial lesions of leukocytoclastic vasculitis (LCV) treated?

What are the treatment options for severe visceral involvement in leukocytoclastic vasculitis (LCV)?

What are the treatment options for chronic leukocytoclastic vasculitis (LCV)?

What are the treatment options for severe or debilitating leukocytoclastic vasculitis (LCV)?

What is the role of rituximab in the treatment of leukocytoclastic vasculitis (LCV)?

When is surgery indicated in the treatment of leukocytoclastic vasculitis (LCV)?

Which specialists should be consulted for the management of leukocytoclastic vasculitis (LCV)?

Which diet modifications helpful in the treatment of leukocytoclastic vasculitis (LCV)?

Medications

What is the role of medication in the treatment of leukocytoclastic vasculitis (LCV)?

Which medications in the drug class Cytotoxic/Immunosuppressive Agents are used in the treatment of Leukocytoclastic Vasculitis?

Which medications in the drug class Corticosteroids are used in the treatment of Leukocytoclastic Vasculitis?

Which medications in the drug class Antibiotics are used in the treatment of Leukocytoclastic Vasculitis?

Which medications in the drug class Anti-inflammatory Agents are used in the treatment of Leukocytoclastic Vasculitis?

Follow-up

What monitoring is needed following treatment of leukocytoclastic vasculitis (LCV)?

When is hospitalization indicated for the treatment of leukocytoclastic vasculitis (LCV)?

How is chronic leukocytoclastic vasculitis (LCV) managed?

What are the transfer indications for patients with leukocytoclastic vasculitis (LCV)?

What is the prognosis of leukocytoclastic vasculitis (LCV)?