Transthyretin-Related Amyloidosis Follow-up

Updated: Jul 19, 2022
  • Author: Jefferson R Roberts, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Complications of transthyretin-related amyloidosis (ATTR) include the following:

  • Familial amyloid polyneuropathy (FAP): Sensory, motor and autonomic neuropathy; cachexia; leptomeningeal involvement
  • Cardiac: Restrictive cardiomyopathy, arrhythmias
  • Renal: End-stage renal disease, nephrotic syndrome
  • Ophthalmologic: Keratoconjunctivitis sicca, glaucoma, vitreous opacities, pupillary abnormalities