Mixed Connective-Tissue Disease Questions & Answers

Updated: Oct 01, 2018
  • Author: Eric L Greidinger, MD; Chief Editor: Herbert S Diamond, MD  more...
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Questions & Answers

Overview

What is mixed connective-tissue disorder (MCTD)?

What is the pathophysiology of mixed connective-tissue disorder (MCTD)?

What causes mixed connective-tissue disorder (MCTD)?

What is the US prevalence of mixed connective-tissue disorder (MCTD)?

What is the global prevalence of mixed connective-tissue disorder (MCTD)?

What is the morbidity and mortality associated with mixed connective-tissue disorder (MCTD)?

What are the racial predilections of mixed connective-tissue disorder (MCTD)?

What are the sexual predilections of mixed connective-tissue disorder (MCTD)?

Which age groups have the highest prevalence of mixed connective-tissue disorder (MCTD)?

What is the prognosis of mixed connective-tissue disorder (MCTD)?

Presentation

Which clinical history findings are characteristic of mixed connective-tissue disorder (MCTD)?

Which physical findings are characteristic of mixed connective-tissue disorder (MCTD)?

DDX

What are the diagnostic criteria for mixed connective-tissue disorder (MCTD)?

Which conditions are included in the differential diagnoses of mixed connective-tissue disorder (MCTD)?

What are the differential diagnoses for Mixed Connective-Tissue Disease?

Workup

What is the role of lab tests in the workup of mixed connective-tissue disorder (MCTD)?

What is the role of antibody studies in the workup of mixed connective-tissue disorder (MCTD)?

Which immune studies are performed in the workup of mixed connective-tissue disorder (MCTD)?

What is the role of imaging studies in the workup of mixed connective-tissue disorder (MCTD)?

What is the role of cardiac tests in the workup of mixed connective-tissue disorder (MCTD)?

What is the role of CFS analysis in the workup of mixed connective-tissue disorder (MCTD)?

What is the role of a six-minute walk test in the workup of mixed connective-tissue disorder (MCTD)?

What is the role of pulmonary function testing in the workup of mixed connective-tissue disorder (MCTD)?

How is hypertension assessed in the workup of mixed connective-tissue disorder (MCTD)?

Treatment

How is mixed connective-tissue disorder (MCTD) treated?

Which specialist consultations are beneficial to patients with mixed connective-tissue disorder (MCTD)?

Which dietary modifications are used in the treatment of mixed connective-tissue disorder (MCTD)?

Which activity modifications are used in the treatment of mixed connective-tissue disorder (MCTD)?

Medications

What is the role of medications in the treatment of mixed connective-tissue disorder (MCTD)?

Which medications in the drug class Cytotoxic agents are used in the treatment of Mixed Connective-Tissue Disease?

Which medications in the drug class Prostaglandins are used in the treatment of Mixed Connective-Tissue Disease?

Which medications in the drug class Endothelin Receptor Antagonist are used in the treatment of Mixed Connective-Tissue Disease?

Which medications in the drug class Phosphodiesterase (type 5) Enzyme Inhibitor are used in the treatment of Mixed Connective-Tissue Disease?

Which medications in the drug class Calcium channel blocking agents are used in the treatment of Mixed Connective-Tissue Disease?

Which medications in the drug class Corticosteroids are used in the treatment of Mixed Connective-Tissue Disease?

Which medications in the drug class Antimalarial agents are used in the treatment of Mixed Connective-Tissue Disease?

Which medications in the drug class Proton pump inhibitors are used in the treatment of Mixed Connective-Tissue Disease?

Which medications in the drug class Cyclooxygenase-2 (COX-2) inhibitors are used in the treatment of Mixed Connective-Tissue Disease?

Which medications in the drug class Nonsteroidal anti-inflammatory drugs (NSAIDs) are used in the treatment of Mixed Connective-Tissue Disease?

Follow-up

What is included in the long-term monitoring of mixed connective-tissue disorder (MCTD)?

When is inpatient care indicated for the treatment of mixed connective-tissue disorder (MCTD)?

What is included in patient education about mixed connective-tissue disorder (MCTD)?