Pancreas Transplantation Workup

Updated: Dec 02, 2015
  • Author: Dixon B Kaufman, MD, PhD; Chief Editor: Ron Shapiro, MD  more...
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Workup

Laboratory Studies

Pretransplantation recipient laboratory evaluation

The pertinent components of a complete pretransplantation recipient medical evaluation are outlined below. The emphasis of the evaluation should be to identify and treat all coexisting medical problems that may increase the rate of morbidity and mortality of the surgical procedure and adversely impact the posttransplantation course. In addition to a thorough medical evaluation, the social issues of the patient should be evaluated to determine conditions that may jeopardize the outcome of transplantation, such as financial and travel restraints or a pattern of noncompliance.

  • Blood chemistries
  • Liver function tests
  • CBC count
  • Coagulation profile

Infectious profile

See the list below:

  • Hepatitis B and Hepatitis C serologies
  • Cytomegalovirus (CMV) serologies (immunoglobulin M/immunoglobulin G [IgM/IgG])
  • Epstein-Barr virus serologies (IgM/IgG)
  • Varicella-zoster serologies (IgM/IgG)
  • Rapid plasma reagin (syphilis)
  • HIV serology
  • Purified protein derivative (tuberculosis skin test with anergy panel, when indicated)

Other

See the list below:

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Imaging Studies

See the list below:

  • Chest radiography (posteroanterior and lateral)
  • Exercise/dipyridamole thallium scintigraphy
  • Coronary arteriography (if indicated)
  • Stress cardiac ultrasonography (if indicated)
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Other Tests

C-peptide level confirms that transplantation candidate has type I diabetes.

A complete cardiac workup, including angiography, is not necessary in every patient. However, individuals with a significant cardiac history, positive review of systems, type I diabetes, or hypertensive renal disease should undergo a complete evaluation to rule out significant coronary artery disease. A 12-lead ECG may be needed prior to transplantation.

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