Lung Transplantation Workup

Updated: Apr 08, 2017
  • Author: Bryan A Whitson, MD, PhD; Chief Editor: Mary C Mancini, MD, PhD, MMM  more...
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Laboratory Studies

Pretransplant laboratory values must be determined to evaluate the appropriateness of the candidate for transplantation. The following are the laboratory tests:

  • HIV, hepatitis B, hepatitis C, toxoplasmosis, cytomegalovirus (CMV), and Epstein-Barr virus (EBV) serologies

  • Liver function tests

  • Creatinine and 24-hour creatinine clearance

  • Complete blood count

  • Chemistry panel

  • Human leukocyte antigen (HLA) phenotype and panel-reactive antibody (PRA) level

  • Cotinine level

  • Room air blood gas

  • Coagulation profile


Imaging Studies

The pretransplant workup includes the following studies:

  • High-resolution chest computed tomographic (CT) scan

  • Echocardiogram

  • Right and left heart catheterization

  • Quantitative lung perfusion scan

  • Mammogram

  • Pap smear/prostate-specific antigen (PSA)

  • Bone density study

  • Pulmonary function tests with a 6-min walk

  • Bronchoscopy