Lung Transplantation Workup

Updated: Apr 08, 2022
  • Author: Bryan A Whitson, MD, PhD; Chief Editor: Mary C Mancini, MD, PhD, MMM  more...
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Laboratory Studies

Pretransplant laboratory values must be determined to evaluate the appropriateness of the candidate for transplantation. The following are the laboratory tests:

  • HIV, hepatitis B, hepatitis C, toxoplasmosis, cytomegalovirus (CMV), and Epstein-Barr virus (EBV) serologies
  • Liver function tests
  • Creatinine and 24-hour creatinine clearance
  • Complete blood count
  • Chemistry panel
  • Human leukocyte antigen (HLA) phenotype and panel-reactive antibody (PRA) level
  • Cotinine level
  • Room air blood gas
  • Coagulation profile

Imaging Studies

The pretransplant workup includes the following studies:

  • High-resolution chest computed tomographic (CT) scan
  • Echocardiogram
  • Right and left heart catheterization
  • Quantitative lung perfusion scan
  • Mammogram
  • Pap smear/prostate-specific antigen (PSA) assay
  • Bone density study
  • Pulmonary function tests with a 6-min walk
  • Bronchoscopy