Epididymitis Questions & Answers

1. Taylor SN. Epididymitis. Clin Infect Dis. 2015 Dec 15. 61 Suppl 8:S770-3. [QxMD MEDLINE Link].

2. Rupp TJ, Leslie SW. Epididymitis. 2020 Jan. [QxMD MEDLINE Link]. [Full Text].

3. [Guideline] Centers for Disease Control and Prevention. Sexually Transmitted Diseases Treatment Guidelines, 2021: Epididymitis. Available at https://www.cdc.gov/std/treatment-guidelines/epididymitis.htm. July 22, 2021; Accessed: May 15, 2022.

4. Trei JS, Canas LC, Gould PL. Reproductive tract complications associated with Chlamydia trachomatis infection in US Air Force males within 4 years of testing. Sex Transm Dis. 2008 Sep. 35(9):827-33. [QxMD MEDLINE Link].

5. Erdem H, Elaldi N, Ak O, Gulsun S, Tekin R, et al. Genitourinary brucellosis: results of a multicentric study. Clin Microbiol Infect. 2014 Nov. 20 (11):O847-53. [QxMD MEDLINE Link]. [Full Text].

6. Santillanes G, Gausche-Hill M, Lewis RJ. Are antibiotics necessary for pediatric epididymitis?. Pediatr Emerg Care. 2011 Mar. 27(3):174-8. [QxMD MEDLINE Link].

7. Raveenthiran V, Sam CJ. Epididymo-orchitis complicating anorectal malformations: collective review of 41 cases. J Urol. 2011 Oct. 186(4):1467-72. [QxMD MEDLINE Link].

8. Goller JL, De Livera AM, Donovan B, Fairley CK, Low N, Hocking JS. Epididymitis rates in Australian hospitals 2009-2018: ecological analysis. Sex Transm Infect. 2020 Jul 29. [QxMD MEDLINE Link].

9. Tanaka K, Ogasawara Y, Nikai K, Yamada S, Fujiwara K, Okazaki T. Acute scrotum and testicular torsion in children: a retrospective study in a single institution. J Pediatr Urol. 2020 Feb. 16 (1):55-60. [QxMD MEDLINE Link].

10. Lorenzo L, Rogel R, Sanchez-Gonzalez JV, Perez-Ardavin J, Moreno E, Lujan S, et al. Evaluation of Adult Acute Scrotum in the Emergency Room: Clinical Characteristics, Diagnosis, Management, and Costs. Urology. 2016 Aug. 94:36-41. [QxMD MEDLINE Link].

11. Siegel A, Snyder H, Duckett JW. Epididymitis in infants and boys: underlying urogenital anomalies and efficacy of imaging modalities. J Urol. 1987 Oct. 138(4 Pt 2):1100-3. [QxMD MEDLINE Link].

12. Hongo H, Kikuchi E, Matsumoto K, Yazawa S, Kanao K, Kosaka T, et al. Novel algorithm for management of acute epididymitis. Int J Urol. 2016 Oct 6. [QxMD MEDLINE Link].

13. Nusbaum MR, Wallace RR, Slatt LM, Kondrad EC. Sexually transmitted infections and increased risk of co-infection with human immunodeficiency virus. J Am Osteopath Assoc. 2004 Dec. 104 (12):527-35. [QxMD MEDLINE Link].

14. Velasquez J, Boniface MP, Mohseni M. Acute Scrotum Pain. 2020 Jan. [QxMD MEDLINE Link]. [Full Text].

15. Sieger N, Di Quilio F, Stolzenburg JU. What is beyond testicular torsion and epididymitis? Rare differential diagnoses of acute scrotal pain in adults: A systematic review. Ann Med Surg (Lond). 2020 Jul. 55:265-274. [QxMD MEDLINE Link]. [Full Text].

16. Tsili AC, Argyropoulou MI, Dolciami M, Ercolani G, Catalano C, Manganaro L. When to ask for an MRI of the scrotum. Andrology. 2021 Sep. 9 (5):1395-1409. [QxMD MEDLINE Link]. [Full Text].

17. Viswaroop BS, Kekre N, Gopalakrishnan G. Isolated tuberculous epididymitis: a review of forty cases. J Postgrad Med. 2005 Apr-Jun. 51(2):109-11, discussion 111. [QxMD MEDLINE Link].

18. Nason GJ, Tareen F, McLoughlin D, McDowell D, Cianci F, Mortell A. Scrotal exploration for acute scrotal pain: A 10-year experience in two tertiary referral paediatric units. Scand J Urol. 2013 Jan 3. [QxMD MEDLINE Link].

19. Rizvi SA, Ahmad I, Siddiqui MA, Zaheer S, Ahmad K. Role of color Doppler ultrasonography in evaluation of scrotal swellings: pattern of disease in 120 patients with review of literature. Urol J. 2011. 8(1):60-5. [QxMD MEDLINE Link].

20. Yu KJ, Wang TM, Chen HW, Wang HH. The dilemma in the diagnosis of acute scrotum: clinical clues for differentiating between testicular torsion and epididymo-orchitis. Chang Gung Med J. 2012 Jan-Feb. 35(1):38-45. [QxMD MEDLINE Link].

21. Waldert M, Klatte T, Schmidbauer J, Remzi M, Lackner J, Marberger M. Color Doppler sonography reliably identifies testicular torsion in boys. Urology. 2010 May. 75(5):1170-4. [QxMD MEDLINE Link].

22. Yusuf G, Sellars ME, Kooiman GG, Diaz-Cano S, Sidhu PS. Global testicular infarction in the presence of epididymitis: clinical features, appearances on grayscale, color Doppler, and contrast-enhanced sonography, and histologic correlation. J Ultrasound Med. 2013 Jan. 32(1):175-80. [QxMD MEDLINE Link].

23. Fehily SR, Trubiano JA, McLean C, Teoh BW, Grummet JP, Cherry CL, et al. Testicular loss following bacterial epididymo-orchitis: Case report and literature review. Can Urol Assoc J. 2015 Mar-Apr. 9 (3-4):E148-51. [QxMD MEDLINE Link]. [Full Text].

24. Siu W, Ohl DA, Schuster TG. Long-term follow-up after epididymectomy for chronic epididymal pain. Urology. 2007 Aug. 70(2):333-5; discussion 335-6. [QxMD MEDLINE Link].

25. Chung JH, Moon HS, Choi HY, et al. Inhibition of Adhesion and Fibrosis Improves the Outcome of Epididymectomy as a Treatment for Chronic Epididymitis: a multicenter, randomized, controlled, single blind study. J Urol. 2012 Dec 3. [QxMD MEDLINE Link].

26. Lee JY, Lee TY, Park HY, Choi HY, Yoo TK, Moon HS. Efficacy of epididymectomy in treatment of chronic epididymal pain: a comparison of patients with and without a history of vasectomy. Urology. 2011 Jan. 77(1):177-82. [QxMD MEDLINE Link].

Christina B Ching, MD Clinical Assistant Professor, Division of Pediatric Urology, Nationwide Children's Hospital

Christina B Ching, MD is a member of the following medical societies: Alpha Omega Alpha, American Medical Student Association/Foundation, American Urological Association

Disclosure: Nothing to disclose.

Edmund S Sabanegh, Jr, MD Chairman, Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic Foundation

Edmund S Sabanegh, Jr, MD is a member of the following medical societies: American Medical Association, American Society of Andrology, Society of Reproductive Surgeons, Society for the Study of Male Reproduction, American Society for Reproductive Medicine, American Urological Association, SWOG

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Edward David Kim, MD, FACS Professor of Urology, Department of Urology, University of Tennessee Graduate School of Medicine; Consulting Staff, University of Tennessee Medical Center

Edward David Kim, MD, FACS is a member of the following medical societies: American Society for Reproductive Medicine, American Urological Association, Sexual Medicine Society of North America, Society for Male Reproduction and Urology, Society for the Study of Male Reproduction, Tennessee Medical Association

Disclosure: Nothing to disclose.

Erik T Goluboff, MD Professor, Department of Urology, College of Physicians and Surgeons, Columbia University College of Physicians and Surgeons; Director of Urology, Allen Pavilion, New York Presbyterian Hospital

Erik T Goluboff, MD is a member of the following medical societies: Alpha Omega Alpha, American Medical Association, American Urological Association, Medical Society of the State of New York, New York Academy of Medicine, Phi Beta Kappa, Society for Basic Urologic Research

Disclosure: Nothing to disclose.

The authors and editors of Medscape Reference gratefully acknowledge the contributions of previous authors Michael Franks, MD, and Badrinath R Konety, MD, to the development and writing of the source article.

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