Urothelial Tumors of the Renal Pelvis and Ureters Questions & Answers

Updated: Jan 15, 2020
  • Author: Kyle A Richards, MD, FACS; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
  • Print
Questions & Answers

Overview

What are urothelial tumors of the renal pelvis and ureters?

What is the prevalence of urothelial tumors of the renal pelvis and ureters?

What causes urothelial tumors of the renal pelvis and ureters?

What are the histologic types of urothelial tumors of the renal pelvis and ureters?

What is the role of molecular mechanisms in the pathophysiology of urothelial tumors of the renal pelvis and ureters?

What are the molecular markers for urothelial tumors of the renal pelvis and ureters?

What is the progression of urothelial tumors of the renal pelvis and ureters?

What is the site distribution of upper tract transitional cell carcinoma (TCC)?

What are the signs and symptoms of urothelial tumors of the renal pelvis and ureters?

When is surgery indicated for urothelial tumors of the renal pelvis and ureters?

What is the anatomy of the kidney relevant to urothelial tumors of the renal pelvis and ureters?

What are the contraindications to surgery for urothelial tumors of the renal pelvis and ureters?

Workup

What is the role of lab tests in the workup of urothelial tumors of the renal pelvis and ureters?

What is the role of imaging studies in the workup of urothelial tumors of the renal pelvis and ureters?

What is the role of CT scanning in the workup of urothelial tumors of the renal pelvis and ureters?

What is the role of 18 F-FDG PET/CT in the workup of urothelial tumors of the renal pelvis and ureters?

What is the role of cytology in the workup of urothelial tumors of the renal pelvis and ureters?

What is the role of fluorescence in situ hybridization (FISH) in the workup of urothelial tumors of the renal pelvis and ureters?

What is the role of ureteroscopy in the workup of urothelial tumors of the renal pelvis and ureters?

How is upper tract transitional cell carcinoma (TCC) diagnosed?

How are urothelial tumors of the renal pelvis and ureters staged?

Treatment

How is upper tract transitional cell carcinoma (TCC) treated?

How are superficial (Ta, T1) and carcinoma in situ urothelial tumors of the renal pelvis and ureters treated?

How are muscle invasive (T2) and locally advanced (T3, T4) urothelial tumors of the renal pelvis and ureters treated?

How are metastatic and node-positive urothelial tumors of the renal pelvis and ureters treated?

What are the EAU guidelines on the treatment of low-risk upper tract urothelial carcinomas?

What is the role of nephroureterectomy in the treatment of urothelial tumors of the renal pelvis and ureters?

What is the role of segmental ureterectomy with ureteral reimplantation in the treatment of urothelial tumors of the renal pelvis and ureters?

What is the role of renal-sparing surgery in the treatment of urothelial tumors of the renal pelvis and ureters?

How is open radical nephroureterectomy performed for the treatment of urothelial tumors of the renal pelvis and ureters?

What are indications for laparoscopic nephroureterectomy in the surgical treatment of urothelial tumors of the renal pelvis and ureters?

What are differences between open and laparoscopic nephroureterectomy in the surgical treatment of urothelial tumors of the renal pelvis and ureters?

What is the role of distal ureterectomy in the surgical treatment of urothelial tumors of the renal pelvis and ureters?

What is the role of ureteroscopy in the treatment of urothelial tumors of the renal pelvis and ureters?

What is the role of percutaneous therapy in the treatment of urothelial tumors of the renal pelvis and ureters?

What are the differences in outcomes between radical nephroureterectomy and conservative, endoscopic management of urothelial tumors of the renal pelvis and ureters?

What is the role of lymph node dissection in the surgical treatment of urothelial tumors of the renal pelvis and ureters?

What is included in the long-term monitoring of urothelial tumors of the renal pelvis and ureters?

What are the possible complications of urothelial tumors of the renal pelvis and ureters?

What are the survival rates for urothelial tumors of the renal pelvis and ureters following total nephroureterectomy?

What is the prognosis of urothelial tumors of the renal pelvis and ureters after treatment?

Which factors are associated with poor prognosis of urothelial tumors of the renal pelvis and ureters?

Which treatments are being investigated for urothelial tumors of the renal pelvis and ureters?

Guidelines

Which organizations have released guidelines on urothelial tumors of the renal pelvis and ureters?

What are the guidelines on the diagnosis of urothelial tumors of the renal pelvis and ureters?

What are the NCCN treatment guidelines for urothelial tumors of the renal pelvis and ureters?

What are the ESMO guidelines on the treatment of on treatment of urothelial tumors of the renal pelvis and ureters?