Hematospermia Questions & Answers

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3. Fletcher MS, Herzberg Z, Pryor JP. The aetiology and investigation of haemospermia. Br J Urol. 1981 Dec. 53(6):669-71. [Medline].

4. Leary FJ, Aguilo JJ. Clinical significance of hematospermia. Mayo Clin Proc. 1974 Nov. 49(11):815-7. [Medline].

5. Ahmad I, Krishna NS. Hemospermia. J Urol. 2007 May. 177(5):1613-8. [Medline].

6. Ganabathi K, Chadwick D, Feneley RC, et al. Haemospermia. Br J Urol. 1992 Mar. 69(3):225-30. [Medline].

7. Berger AP, Gozzi C, Steiner H, et al. Complication rate of transrectal ultrasound guided prostate biopsy: a comparison among 3 protocols with 6, 10 and 15 cores. J Urol. 2004 Apr. 171(4):1478-80; discussion 1480-1. [Medline].

8. Manoharan M, Ayyathurai R, Nieder AM, Soloway MS. Hemospermia following transrectal ultrasound-guided prostate biopsy: a prospective study. Prostate Cancer and Prostatic Diseases. 2/20/2007. 10:283-287. [Medline]. [Full Text].

9. Ambakederemo TE, Dodiyi-Manuel ST, Ebuenyi ID. Bloody semen, severe hypertension and a worried man. Pan Afr Med J. 2015. 20:326. [Medline].

10. Han M, Brannigan RE, Antenor JA, et al. Association of hemospermia with prostate cancer. J Urol. 2004 12. 172(6, Part 1 of 2):2189-2192. [Medline].

11. Prando A. Endorectal magnetic resonance imaging in persistent hemospermia. Int Braz J Urol. 2008 Mar-Apr. 34(2):171-7; discussion 177-9. [Medline].

12. Ng YH, Seeley JP, Smith G. Haematospermia as a presenting symptom: outcomes of investigation in 300 men. Surgeon. 2013 Feb. 11(1):35-8. [Medline].

13. Etherington RJ, Clements R, Griffiths GJ, et al. Transrectal ultrasound in the investigation of haemospermia. Clin Radiol. 1990 Mar. 41(3):175-7. [Medline].

14. Furuya S, Kato H. A clinical entity of cystic dilatation of the utricle associated with hemospermia. J Urol. 2005 Sep. 174(3):1039-42. [Medline].

15. Abdelkhalek MA, Abdelshafy M, Elhelaly HA, El Nasr MK. Hemospermia after transrectal ultrasound (TRUS)-guided prostatic biopsy: a prospective study. J Egypt Soc Parasitol. 2012 Apr. 42(1):63-70. [Medline].

16. Finney G, Haynes AM, Cross P, et al. Cross-sectional analysis of sexual function after prostate brachytherapy. Urology. 2005 Aug. 66(2):377-81. [Medline].

17. Walsh IK, Keane PF, Herron B. Benign urethral polyps. Br J Urol. 1993 Dec. 72(6):937-8. [Medline].

18. Furuya S, Masumori N, Furuya R, et al. Characterization of localized seminal vesicle amyloidosis causing hemospermia: an analysis using immunohistochemistry and magnetic resonance imaging. J Urol. 2005 Apr. 173(4):1273-7. [Medline].

19. Koment RW, Poor PM. Infection by human cytomegalovirus associated with chronic hematospermia. Urology. 1983 Dec. 22(6):617-21. [Medline].

20. Yu HH, Wong KK, Lim TK, et al. Clinical study of hemospermia. Urology. 1977 Dec. 10(6):562-3. [Medline].

21. Bamberger E, Madeb R, Steinberg J, et al. Detection of sexually transmitted pathogens in patients with hematospermia. Isr Med Assoc J. 2005 Apr. 7(4):224-7. [Medline].

22. Shebel HM, Elsayes KM, Abou El Atta HM, Elguindy YM, El-Diasty TA. Genitourinary schistosomiasis: life cycle and radiologic-pathologic findings. Radiographics. 2012 Jul-Aug. 32 (4):1031-46. [Medline].

23. Downs JA, de Dood CJ, Dee HE, McGeehan M, Khan H, Marenga A, et al. Schistosomiasis and Human Immunodeficiency Virus in Men in Tanzania. Am J Trop Med Hyg. 2017 Apr. 96 (4):856-862. [Medline].

24. Whyman MR, Morris DL. Retrovesical hydatid causing haemospermia. Br J Urol. 1991 Jul. 68(1):100-1. [Medline].

25. Radfar MH, Simforoosh N, Sotoudeh M, Ramezani MH, Mollakoochakian MJ, Nikravesh M, et al. What is the impact of extracorporeal shock wave lithotripsy on semen parameters? A systematic review and meta-analysis. Urologia. 2017 Feb 3. 84 (1):28-34. [Medline].

26. Lemesh RA. Case report: recurrent hematuria and hematospermia due to prostatic telangiectasia in classic von Willebrand's disease. Am J Med Sci. 1993 Jul. 306(1):35-6. [Medline].

27. Minardi D, Scortechini AR, Milanese G, Leoni P, Muzzonigro G. Spontaneous recurrent hematuria and hematospermia: Unique manifestations of von Willebrand disease type I. Case report. Arch Ital Urol Androl. 2016 Mar 31. 88 (1):62-3. [Medline].

28. Close CF, Yeo WW, Ramsay LE. The association between haemospermia and severe hypertension. Postgrad Med J. 1991 Feb. 67(784):157-8. [Medline].

29. Kurkar A, Elderwy AA, Awad SM, Abulsorour S, Aboul-Ella HA, Altaher A. Hyperuricemia: a possible cause of hemospermia. Urology. 2014 Sep. 84(3):609-12. [Medline].

30. [Guideline] Davis R, Jones JS, Barocas DA, Castle EP, Lang EK, Leveillee RJ, et al. Diagnosis, evaluation and follow-up of asymptomatic microhematuria (AMH) in adults: AUA guideline. J Urol. 2012 Dec. 188 (6 Suppl):2473-81. [Medline]. [Full Text].

31. Smith GW, Griffith DP, Pranke DW. Melanospermia: an unusual presentation of malignant melanoma. J Urol. 1973 Sep. 110(3):314-6. [Medline].

32. Xing C, Zhou X, Xin L, Hu H, Li L, Fang J, et al. Prospective trial comparing transrectal ultrasonography and transurethral seminal vesiculoscopy for persistent hematospermia. Int J Urol. 2012 May. 19(5):437-42. [Medline].

33. Worischeck JH, Parra RO. Chronic hematospermia: assessment by transrectal ultrasound. Urology. 1994 Apr. 43(4):515-20. [Medline].

34. Raviv G, Laufer M, Miki H. Hematospermia--the added value of transrectal ultrasound to clinical evaluation: is transrectal ultrasound necessary for evaluation of hematospermia?. Clin Imaging. 2013 Sep-Oct. 37(5):913-6. [Medline].

35. Maeda H, Toyooka N, Kinukawa T, et al. Magnetic resonance images of hematospermia. Urology. 1993 May. 41(5):499-504. [Medline].

36. Yang SC, Rha KH, Byon SK, et al. Transutricular seminal vesiculoscopy. J Endourol. 2002 Aug. 16(6):343-5. [Medline].

37. Oh TH, Seo IY. Endoscopic Treatment for Persistent Hematospermia: A Novel Technique Using a Holmium Laser. Scand J Surg. 2015 Oct 22. 16:270-1. [Medline].

38. Fuse H, Sumiya H, Ishii H, et al. Treatment of hemospermia caused by dilated seminal vesicles by direct drug injection guided by ultrasonography. J Urol. 1988 Nov. 140(5):991-2. [Medline].

39. Li L, Jiang C, Song C, et al. Transurethral endoscopy technique with a ureteroscope for diagnosis and management of seminal tracts disorders: a new approach. J Endourol. 2008 Apr. 22(4):719-24. [Medline].

40. Li YF, Liang PH, Sun ZY, Zhang Y, Bi G, Zhou B, et al. Imaging diagnosis, transurethral endoscopic observation, and management of 43 cases of persistent and refractory hematospermia. J Androl. 2012 Sep. 33(5):906-16. [Medline].

41. Shen BY, Chang PL, Lee SH, Chen CL, Tsui KH. Complications following combined transrectal ultrasound-guided prostate needle biopsies and transurethral resection of the prostate. Arch Androl. 2006 Mar-Apr. 52(2):123-7. [Medline].

42. Collins GN, Lloyd SN, Hehir M, et al. Multiple transrectal ultrasound-guided prostatic biopsies--true morbidity and patient acceptance. Br J Urol. 1993 Apr. 71(4):460-3. [Medline].

43. Craig SR. 3-in-1' nerve block complicated by haemospermia. Br J Clin Pract. 1992 Summer. 46(2):80. [Medline].

44. Geoghegan JG, Bonavia I. Haemospermia as a presenting symptom of lymphoma. Br J Urol. 1990 Dec. 66(6):658. [Medline].

45. Gustafsson O, Norming U, Nyman CR, et al. Complications following combined transrectal aspiration and core biopsy of the prostate. Scand J Urol Nephrol. 1990. 24(4):249-51. [Medline].

46. Kawahara M, Matsuhashi M, Tajima M, et al. Primary carcinoma of seminal vesicle. Diagnosis assisted by sonography. Urology. 1988 Sep. 32(3):269-72. [Medline].

47. Stein AJ, Prioleau PG, Catalona WJ. Adenomatous polyps of the prostatic urethra: a cause of hematospermia. J Urol. 1980 Aug. 124(2):298-9. [Medline].

48. Weidner W, Jantos C, Schumacher F, et al. Recurrent haemospermia--underlying urogenital anomalies and efficacy of imaging procedures. Br J Urol. 1991 Mar. 67(3):317-23. [Medline].

49. Benson, RC Jr., Clark WR, Farrow GM. Carcinoma of the Seminal Vesicle. Journal of Urology. September 1984. 123 (3):483-485. [Medline]. [Full Text].

Alexander D Tapper, MD Resident Physician, Department of Urology, William Beaumont Hospital

Alexander D Tapper, MD is a member of the following medical societies: Alpha Omega Alpha, American Medical Association, American Urological Association, Michigan State Medical Society

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Edward David Kim, MD, FACS Professor of Surgery, Division of Urology, University of Tennessee Graduate School of Medicine; Consulting Staff, University of Tennessee Medical Center

Edward David Kim, MD, FACS is a member of the following medical societies: American College of Surgeons, American Society for Reproductive Medicine, American Society of Andrology, American Urological Association, Sexual Medicine Society of North America, Tennessee Medical Association

Disclosure: Serve(d) as a speaker or a member of a speakers bureau for: Endo.

Edmund S Sabanegh, Jr, MD Chairman, Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic Foundation

Edmund S Sabanegh, Jr, MD is a member of the following medical societies: American Medical Association, American Society of Andrology, Society of Reproductive Surgeons, Society for the Study of Male Reproduction, American Society for Reproductive Medicine, American Urological Association, SWOG

Disclosure: Nothing to disclose.

John P Mulhall, MD Director, Sexual and Reproductive Medicine Program, Memorial Sloan-Kettering Cancer Center

John P Mulhall, MD is a member of the following medical societies: American Society for Reproductive Medicine, American Society of Andrology, American Urological Association, Society for Basic Urologic Research, Society of University Urologists

Disclosure: Nothing to disclose.

Jonathan D Schiff, MD Assistant Clinical Professor of Urology, Department of Urology, Mount Sinai Medical Center; Adjunct Assistant Clinical Professor of Urology, Weill-Cornell School of Medicine

Jonathan D Schiff, MD is a member of the following medical societies: American Urological Association

Disclosure: Nothing to disclose.

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