Transrectal Ultrasonography of the Prostate Questions & Answers

1. Rullis I, Shaeffer JA, Lilien OM. Incidence of prostatic carcinoma in the elderly. Urology. 1975 Sep. 6 (3):295-7. [QxMD MEDLINE Link].

2. Thompson I, Thrasher JB, Aus G, et al. Guidelines for the Management of Clinically Localized Prostate Cancer (2007). American Urological Association. Available at https://www.auanet.org/education/guidelines/prostate-cancer.cfm. 2009; Accessed: June 12, 2016.

3. Guideline developed in collaboration with the American College of Radiology, Society of Radiologists in Ultrasound. AIUM Practice Guideline for the Performance of an Ultrasound Evaluation of the Prostate (and Surrounding Structures). J Ultrasound Med. 2015 Aug. 34 (8):1-6. [QxMD MEDLINE Link].

4. [Guideline] American Cancer Society Cancer Facts & Figures 2019. American Cancer Society. Available at https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2019/cancer-facts-and-figures-2019.pdf.. 2019; Accessed: : March 26, 2019.

5. Auffenberg GB, Meeks JJ. Application of the 2013 American Urological Association early detection of prostate cancer guideline: Who will we miss?. World J Urol. 2014 Jun 20. [QxMD MEDLINE Link].

6. Ragde H, Kenny GM, Murphy GP, Landin K. Transrectal ultrasound microbubble contrast angiography of the prostate. Prostate. 1997 Sep 1. 32(4):279-83. [QxMD MEDLINE Link].

7. Watanabe A, Otake R, Nozaki T, Morii A, Ogawa R, Fujimoto S, et al. Effects of microbubbles on ultrasound-mediated gene transfer in human prostate cancer PC3 cells: comparison among Levovist, YM454, and MRX-815H. Cancer Lett. 2008 Jun 28. 265(1):107-12. [QxMD MEDLINE Link].

8. Halpern EJ, Verkh L, Forsberg F, et al. Initial experience with contrast-enhanced sonography of the prostate. AJR Am J Roentgenol. 2000 Jun. 174(6):1575-80. [QxMD MEDLINE Link].

9. Gelet A, Chapelon JY. Effects of high intensity focussed ultrasound on malignant cells and tissues. Maberger, ed. Application of Newer Forms of Therapeutic Energy in Urology. Oxford ISIS; 1995. 107-14.

10. Thüroff S, Chaussy C, Vallancien G, Wieland W, Kiel HJ, Le Duc A. High-intensity focused ultrasound and localized prostate cancer: efficacy results from the European multicentric study. J Endourol. 2003 Oct. 17(8):673-7. [QxMD MEDLINE Link].

11. Gelet A, Chapelon JY, Poissonnier L, Bouvier R, Rouvière O, Curiel L. Local recurrence of prostate cancer after external beam radiotherapy: early experience of salvage therapy using high-intensity focused ultrasonography. Urology. 2004 Apr. 63(4):625-9. [QxMD MEDLINE Link].

12. Krouskop TA, Wheeler TM, Kallel F, Garra BS, Hall T. Elastic moduli of breast and prostate tissues under compression. Ultrason Imaging. 1998 Oct. 20(4):260-74. [QxMD MEDLINE Link].

13. König K, Scheipers U, Pesavento A, Lorenz A, Ermert H, Senge T. Initial experiences with real-time elastography guided biopsies of the prostate. J Urol. 2005 Jul. 174(1):115-7. [QxMD MEDLINE Link].

14. Correas JM, Tissier AM, Khairoune A, Khoury G, Eiss D, Hélénon O. Ultrasound elastography of the prostate: state of the art. Diagn Interv Imaging. 2013 May. 94 (5):551-60. [QxMD MEDLINE Link].

15. Correas JM, Tissier AM, Khairoune A, Vassiliu V, Méjean A, Hélénon O, et al. Prostate cancer: diagnostic performance of real-time shear-wave elastography. Radiology. 2015 Apr. 275 (1):280-9. [QxMD MEDLINE Link].

16. Miyanaga N, Akaza H, Yamakawa M, Oikawa T, Sekido N, Hinotsu S, et al. Tissue elasticity imaging for diagnosis of prostate cancer: a preliminary report. Int J Urol. 2006 Dec. 13(12):1514-8. [QxMD MEDLINE Link].

17. Pallwein L, Mitterberger M, Gradl J, Aigner F, Horninger W, Strasser H, et al. Value of contrast-enhanced ultrasound and elastography in imaging of prostate cancer. Curr Opin Urol. 2007 Jan. 17(1):39-47. [QxMD MEDLINE Link].

18. Pallwein L, Mitterberger M, Struve P, Horninger W, Aigner F, Bartsch G, et al. Comparison of sonoelastography guided biopsy with systematic biopsy: impact on prostate cancer detection. Eur Radiol. 2007 Sep. 17(9):2278-85. [QxMD MEDLINE Link].

19. Salomon G, Graefen M, Heinzer H, Huland H, Pallwein L, Aigner F, et al. [The value of real-time elastography in the diagnosis of prostate cancer]. Urologe A. 2009 Jun. 48(6):628-36. [QxMD MEDLINE Link].

20. Sonn GA, Margolis DJ, Marks LS. Target detection: Magnetic resonance imaging-ultrasound fusion-guided prostate biopsy. Urol Oncol. 2013 Nov 13. [QxMD MEDLINE Link]. [Full Text].

21. Sonn GA, Natarajan S, Margolis DJ, MacAiran M, Lieu P, Huang J, et al. Targeted biopsy in the detection of prostate cancer using an office based magnetic resonance ultrasound fusion device. J Urol. 2013 Jan. 189(1):86-91. [QxMD MEDLINE Link]. [Full Text].

22. Vourganti S, Rastinehad A, Yerram NK, Nix J, Volkin D, Hoang A, et al. Multiparametric magnetic resonance imaging and ultrasound fusion biopsy detect prostate cancer in patients with prior negative transrectal ultrasound biopsies. J Urol. 2012 Dec. 188(6):2152-7. [QxMD MEDLINE Link]. [Full Text].

23. Puech P, Rouvière O, Renard-Penna R, Villers A, Devos P, Colombel M, et al. Prostate cancer diagnosis: multiparametric MR-targeted biopsy with cognitive and transrectal US-MR fusion guidance versus systematic biopsy--prospective multicenter study. Radiology. 2013 Aug. 268(2):461-9. [QxMD MEDLINE Link].

24. Ahmed HU, El-Shater Bosaily A, Brown LC, et al. Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study. Lancet. 2017 Feb 25. 389(10071):815-822. [QxMD MEDLINE Link]. [Full Text].

25. Tafuri A, Ashrafi AN, Palmer S, Shakir A, Cacciamani GE, Iwata A, et al. One-Stop MRI and MRI/transrectal ultrasound fusion-guided biopsy: an expedited pathway for prostate cancer diagnosis. World J Urol. 2019 Jun 7. [QxMD MEDLINE Link].

26. Boesen L. Magnetic resonance imaging-transrectal ultrasound image fusion guidance of prostate biopsies: current status, challenges and future perspectives. Scand J Urol. 2019 Apr 22. 1-8. [QxMD MEDLINE Link].

27. Delongchamps NB, Peyromaure M, Schull A, Beuvon F, Bouazza N, Flam T, et al. Prebiopsy magnetic resonance imaging and prostate cancer detection: comparison of random and targeted biopsies. J Urol. 2013 Feb. 189(2):493-9. [QxMD MEDLINE Link].

28. Rosenkrantz AB, Verma S, Choyke P, et al. Prostate MRI and MRI-Targeted Biopsy in Patients with Prior Negative Biopsy. American Urological Associations. Available at https://www.auanet.org/common/pdf/education/clinical-guidance/Consensus-Statement-Prostate-MRI-and-MRI-Targeted-Biopsy.pdf. June 2016; Accessed: June 12, 2016.

29. Weinreb JC, Barentsz JO, choyke PL, et al. Prostate Imaging Reporting and Data System (PI-RADS). American College of Radiology. Available at http://www.acr.org/Quality-Safety/Resources/PIRADS. 2016; Accessed: June 14, 2016.

30. Kasivisvanathan V, Rannikko AS, Borghi M, et al. MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis. N Engl J Med. 2018 May 10. 10;378(19):1767-1777. [QxMD MEDLINE Link]. [Full Text].

31. Amin MB, de-Peralta Venturina M, Killeen TC. Pathological significance of the invaginated extraprostatic space involvement by prostatic carcinoma. A study of 80 cases of stage T3b prostatic carcinoma. Mod Pathol. 2005. 18 (supplement 1):126 A.

32. Gill IS, Ukimura O. Thermal energy-free laparoscopic nerve-sparing radical prostatectomy: one-year potency outcomes. Urology. 2007 Aug. 70(2):309-14. [QxMD MEDLINE Link].

33. Taylor AK, Zembower TR, Nadler RB, Scheetz MH, Cashy JP, Bowen D, et al. Targeted Antimicrobial Prophylaxis Using Rectal Swab Cultures in Men Undergoing Transrectal Ultrasound Guided Prostate Biopsy is Associated With Reduced Incidence of Postoperative Infectious Complications and Cost of Care. J Urol. 2012 Feb 15. [QxMD MEDLINE Link].

34. Pareek G, Armenakas NA, Fracchia JA. Periprostatic nerve blockade for transrectal ultrasound guided biopsy of the prostate: a randomized, double-blind, placebo controlled study. J Urol. 2001 Sep. 166(3):894-7. [QxMD MEDLINE Link].

35. Alavi AS, Soloway MS, Vaidya A, Lynne CM, Gheiler EL. Local anesthesia for ultrasound guided prostate biopsy: a prospective randomized trial comparing 2 methods. J Urol. 2001 Oct. 166(4):1343-5. [QxMD MEDLINE Link].

36. Mutaguchi K, Shinohara K, Matsubara A, et al. Local anesthesia during 10 core biopsy of the prostate: comparison of 2 methods. J Urol. 2005 Mar. 173(3):742-5. [QxMD MEDLINE Link].

37. Cantiello F, Cicione A, Autorino R, Cosentino C, Amato F, Damiano R. Pelvic Plexus Block is More Effective than Periprostatic Nerve Block for Pain Control During Office Transrectal Ultrasound Guided Prostate Biopsy: A Single Center, Prospective, Randomized, Double Arm Study. J Urol. 2012 Aug. 188(2):417-22. [QxMD MEDLINE Link].

38. Pinkhasov GI, Lin YK, Palmerola R, Smith P, Mahon F, Kaag MG, et al. Complications following prostate needle biopsy requiring hospital admission or emergency department visits - experience from 1000 consecutive cases. BJU Int. 2012 Feb 7. [QxMD MEDLINE Link].

39. Davis BJ, Horwitz EM, Lee WR, Crook JM, Stock RG, Merrick GS, et al. American Brachytherapy Society consensus guidelines for transrectal ultrasound-guided permanent prostate brachytherapy. Brachytherapy. 2012 Jan. 11(1):6-19. [QxMD MEDLINE Link].

40. Cohen JK, Miller RJ Jr, Rooker GM. Four year PSA and biopsy results after cryosurgical ablation of the prostate for localized adenocarcinoma of the prostate. J Urol. 1997. 157:419.

41. Ghafar MA, Johnson CW, De La Taille A, et al. Salvage cryotherapy using an argon based system for locally recurrent prostate cancer after radiation therapy: the Columbia experience. J Urol. 2001 Oct. 166(4):1333-7; discussion 1337-8. [QxMD MEDLINE Link].

42. Portalez D, Mozer P, Cornud F, Renard-Penna R, Misrai V, Thoulouzan M, et al. Validation of the European Society of Urogenital Radiology scoring system for prostate cancer diagnosis on multiparametric magnetic resonance imaging in a cohort of repeat biopsy patients. Eur Urol. 2012 Dec. 62(6):986-96. [QxMD MEDLINE Link].

43. Eure G, Fanney D, Lin J, Wodlinger B, Ghai S. Comparison of conventional transrectal ultrasound, magnetic resonance imaging, and micro-ultrasound for visualizing prostate cancer in an active surveillance population: A feasibility study. Can Urol Assoc J. 2019 Mar. 13 (3):E70-E77. [QxMD MEDLINE Link].

Sugandh Shetty, MD, FRCS Associate Professor of Urology, Oakland University William Beaumont School of Medicine; Attending Physician, Department of Urology, William Beaumont Hospital

Sugandh Shetty, MD, FRCS is a member of the following medical societies: American Urological Association

Disclosure: Nothing to disclose.

Kassem Faraj Oakland University William Beaumont School of Medicine

Kassem Faraj is a member of the following medical societies: American Medical Association, American Medical Student Association/Foundation, American Urological Association, Michigan State Medical Society

Disclosure: Nothing to disclose.

Zubin Shetty, MSc Wayne State University School of Medicine

Zubin Shetty, MSc is a member of the following medical societies: American Medical Association, Michigan State Medical Society

Disclosure: Nothing to disclose.

Paul Sutcliffe, BS State University of New York Upstate Medical University

Paul Sutcliffe, BS is a member of the following medical societies: American Medical Student Association/Foundation

Disclosure: Nothing to disclose.

Chirag N Dave, MD Physician in Sexual and Male Reproductive Medicine and Urology, Advanced Urology Institute of Georgia

Chirag N Dave, MD is a member of the following medical societies: American Urological Association, Sexual Medicine Society of North America

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Bradley Fields Schwartz, DO, FACS Professor of Urology, Director, Center for Laparoscopy and Endourology, Department of Surgery, Southern Illinois University School of Medicine

Bradley Fields Schwartz, DO, FACS is a member of the following medical societies: American College of Surgeons, American Urological Association, Association of Military Osteopathic Physicians and Surgeons, Endourological Society, Society of Laparoendoscopic Surgeons, Society of University Urologists

Disclosure: Serve(d) as a director, officer, partner, employee, advisor, consultant or trustee for: Endourological Society Board of Directors; President Elect North Central Section of the American Urological Association<br/>Serve(d) as a speaker or a member of a speakers bureau for: Cook Medical.

Martha K Terris, MD, FACS Professor and Chief of Urology, Witherington Distinguished Chair, Department of Surgery, Section of Urology, Director, Urology Residency Training Program, Medical College of Georgia at Augusta University; Professor, Department of Physician Assistants, Medical College of Georgia School of Allied Health; Chief, Section of Urology, Augusta Veterans Affairs Medical Center

Martha K Terris, MD, FACS is a member of the following medical societies: American Cancer Society, American College of Surgeons, American Institute of Ultrasound in Medicine, American Society of Clinical Oncology, American Urological Association, Association of Women Surgeons, New York Academy of Sciences, Society of Government Service Urologists, Society of University Urologists, Society of Urology Chairpersons and Program Directors, Society of Women in Urology

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Reference Salary Employment

Martha K Terris, MD, FACS Professor, Department of Surgery, Section of Urology, Director, Urology Residency Training Program, Medical College of Georgia; Professor, Department of Physician Assistants, Medical College of Georgia School of Allied Health; Chief, Section of Urology, Augusta Veterans Affairs Medical Center

Martha K Terris, MD, FACS is a member of the following medical societies: American Cancer Society, American College of Surgeons, American Institute of Ultrasound in Medicine, American Society of Clinical Oncology, American Urological Association, Association of Women Surgeons, New York Academy of Sciences, Society of Government Service Urologists, Society of University Urologists, Society of Urology Chairpersons and Program Directors, and Society of Women in Urology

Disclosure: Nothing to disclose.

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