Octopus Envenomation Medication

Updated: Jun 18, 2018
  • Author: Jon Mark Hirshon, MD, MPH, PhD, FACEP; Chief Editor: Joe Alcock, MD, MS  more...
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Medication Summary

The goal of pharmacotherapy is to reduce morbidity and prevent complications. Administration of nondepolarizing neuromuscular blocking antagonists may be beneficial. 4-Aminopyridine (Neurelan) is utilized as an antagonist to nondepolarizing neuromuscular blocking agents (available in the United States as an orphan drug for multiple sclerosis), has been shown to reverse tetrodotoxin toxicity in animal experiments. [2, 17] The dosing regimen for use in octopus envenomation is not yet established.