Brown Snake Envenomation Workup

Updated: May 12, 2017
  • Author: David Cheng, MD; Chief Editor: Joe Alcock, MD, MS  more...
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Workup

Laboratory Studies

Laboratory studies can include the following:

  • Complete blood cell (CBC) count
  • Prothrombin time (PT)/activated partial thromboplastin time (aPTT)/international normalized ratio (INR) - Mild envenomation INR greater than 2; complete defibrination INR greater than 12 [8]
  • Fibrinogen - Severe envenomation associated with afibrinogenemia (<0.3 g/L)
  • Fibrin degradation products
  • D-dimer
  • Electrolytes
  • Blood urea nitrogen (BUN) and creatinine
  • Urinalysis
  • Type and crossmatch for packed red blood cells (PRBCs), fresh frozen plasma (FFP), and platelets
  • CSL commercial snake venom qualitative detection kit
  • Enzyme immunoassays (EIAs) for quantifying venom concentration: A small study of 27 brown snake envenomed patients showed the median venom concentration was 20 ng/mL. The EIA test is able to detect down to concentrations of 3 ng/mL. [9]
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Imaging Studies

Imaging studies may include chest radiography and computed tomography (CT) scan of the head if intracranial hemorrhage is suspected.

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Other Tests

Electrocardiogram (ECG) may be necessary.

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