Idiopathic Thrombocytopenic Purpura (ITP) in Emergency Medicine Differential Diagnoses

Updated: Nov 05, 2017
  • Author: Michael A Silverman, MD, MD; Chief Editor: Gil Z Shlamovitz, MD, FACEP  more...
  • Print

Diagnostic Considerations

Other problems to be considered in the differential diagnosis include the following:

  • Pseudothrombocytopenia (platelet clumping in the presence of ethylenediaminetetraacetic acid [EDTA])
  • Liver disease
  • Myelodysplasia
  • Lymphoproliferative, autoimmune, or infectious diseases
  • Pregnancy-associated thrombocytopenia
  • Drug-induced immune thrombocytopenia (alcohol, heparin, quinine/quinidine, sulfonamides)
  • Infection/sepsis
  • Acute leukemia
  • Myelodysplastic syndrome
  • Malignancy
  • Megaloblastic anemia
  • Isoimmune neonatal purpura
  • Transfusion
  • Factitious

Differential Diagnoses