Transfusion Reactions in Emergency Medicine Questions & Answers

Updated: Dec 24, 2020
  • Author: Ross A Wanner, MD; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Questions & Answers

Overview

What is the range of blood transfusion reactions in the emergency department (ED)?

What is the pathophysiology of hemolytic transfusion reactions?

What is the pathophysiology of nonhemolytic febrile transfusion reactions?

What is the pathophysiology of anaphylactic transfusion reactions?

Can infections be transmitted through transfusion?

What is the pathophysiology of graft-versus-host (GVH) disease from transfusions?

What is the pathophysiology of transfusion-related acute lung injury?

What are the possible complications of massive transfusion?

What is the prevalence of adverse transfusion reactions?

What is the mortality and morbidity associated with adverse transfusion reactions?

What are the sexual predilections of adverse transfusion reactions?

Which age groups are at higher risk of developing transfusion-related HIV?

Presentation

Which clinical history findings are characteristic of nonhemolytic febrile transfusion reactions?

Which clinical history findings are characteristic of allergic and anaphylactic transfusion reactions?

Which clinical history findings are characteristic of extravascular hemolytic transfusion reactions?

Which clinical history findings are characteristic of transfusion-related acute lung injury?

Which clinical history findings are characteristic of transfusion-related GVH disease?

Which clinical history findings are characteristic of transfusion-related hypocalcemia?

Which clinical history findings are characteristic of hemolytic transfusion reactions?

Which physical findings are characteristic of nonhemolytic febrile transfusion reactions?

Which physical findings are characteristic of anaphylactic transfusion reactions?

Which physical findings are characteristic of extravascular hemolytic transfusion reactions?

Which physical findings are characteristic of transfusion-related acute lung injury?

Which physical findings are characteristic of transfusion-related GVH disease?

Which physical findings are characteristic of hemolytic transfusion reactions?

What causes transfusion-related infectious diseases?

DDX

What are the differential diagnoses for Transfusion Reactions in Emergency Medicine?

Workup

What is the role of lab tests in the workup of adverse transfusion reactions?

What is the role of radiography in the workup of adverse transfusion reactions?

What is the role of ECG in the workup of adverse transfusion reactions?

What is the role of catheters in the workup of adverse transfusion reactions?

What is the role of endotracheal intubation in the workup of adverse transfusion reactions?

Treatment

How are adverse transfusion reactions treated?

How are adverse reactions of massive transfusion treated?

Medications

What is the role of medications in the treatment of adverse transfusion reactions?

Which medications in the drug class Corticosteroids are used in the treatment of Transfusion Reactions in Emergency Medicine?

Which medications in the drug class Antihistamines are used in the treatment of Transfusion Reactions in Emergency Medicine?

Which medications in the drug class Vasopressors are used in the treatment of Transfusion Reactions in Emergency Medicine?

Which medications in the drug class Diuretics are used in the treatment of Transfusion Reactions in Emergency Medicine?

Follow-up

What is included in inpatient care for adverse transfusion reactions?

How are adverse transfusion reactions prevented?

What are the possible complications of adverse transfusion reactions?

What is included in patient education about adverse transfusion reactions?