Condyloma Acuminatum (Genital Warts) Workup

Updated: Sep 30, 2020
  • Author: Delaram Ghadishah, MD; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Workup

Laboratory Studies

As indicated by history and examination, test for other STDs, such as HIV, gonorrhea, chlamydia, and syphilis.

Although not ED tests, the following are listed strictly for educational purposes and to assist readers in understanding and managing potential complications:

  • Pap smear: This test is used to look for papillomatosis, acanthosis, koilocytic abnormality, and mild nuclear abnormality.

  • Filter hybridization (Southern blot and slot blot hybridization), in situ hybridization, and polymerase chain reaction (PCR): These tests may be used for diagnosis and HPV typing.

  • Hybrid capture

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Other Tests

Acetowhitening: Subclinical lesions can be visualized by wrapping penis with gauze soaked with 5% acetic acid for 5 minutes. Using a 10-X hand lens or colposcope, warts appear as tiny white papules. A shiny white appearance of skin represents foci of epithelial hyperplasia (subclinical infection).

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Procedures

Although not ED procedures, the following are listed strictly for educational purposes and to assist readers in understanding and managing potential presenting complications:

  • Colposcopy (stereoscopic microscopy): This is very useful to identify (mostly) cervical lesions, which are identified better using acetic acid.

  • Biopsy: Biopsy is indicated for lesions that are atypical, recurrent after initial success, or resistant to treatment or in patients with a high risk for neoplasia or immunosuppression.

  • Anoscopy

  • Antroscopy

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