Lymphogranuloma Venereum (LGV) in Emergency Medicine Follow-up

Updated: Apr 02, 2021
  • Author: Kristyn J Smith, DO; Chief Editor: Jeter (Jay) Pritchard Taylor, III, MD  more...
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Infection confers little or no protective immunity against future infection.

Sexual contacts should be referred for evaluation, testing, and empiric treatment with an anti-chlamydia regimen (doxycycline 100mg orally twice a day for 7 days) possible treatment. If tests return positive the duration of doxycycline should be extended to the full 21 day regimen. 

Encourage the practice of safe sex.



Secondary lymphogranuloma venereum (LGV): Bubonuli may rupture to form sinuses or fistulas. This may result in long-term complications, including fibrosis and deforming scars at the penile base. In women, cervicitis, perimetritis, or salpingitis may occur.

Tertiary LGV: Complete bowel obstruction from an anal stricture may occur. Bowel perforation from chronic rectal inflammation and scarring may develop. 

Other complications of LGV: arthritis, conjunctivitis, hepatomegaly and, rarely, pericarditis, pneumonia, and meningoencephalitis.



Generally, full recovery is expected with appropriate treatment, especially when treated during the primary or secondary stages. 

Reinfection and relapse may occur.


Patient Education

For excellent patient education resources, visit eMedicineHealth's patient education articles on Sexually Transmitted Diseases, How to Use a CondomBirth Control, and Chlamydia.