Lymphogranuloma Venereum (LGV) in Emergency Medicine Guidelines

Updated: May 23, 2017
  • Author: Jesse Tran, DO; Chief Editor: Jeter (Jay) Pritchard Taylor, III, MD  more...
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Guidelines

WHO Guidelines on the Treatment of Lymphogranuloma Venereum

WHO recommendations for the treatment of lymphogranuloma venereum (LGV) are as follows: [10]

  • In adults and adolescents with LGV, the guidelines suggest doxycycline 100 mg orally twice daily for 21 days over azithromycin 1 g orally weekly for 3 weeks.
  • Good practice dictates treatment of LGV, particularly for men who have sex with men and for people with HIV infection.
  • When doxycycline is contraindicated, azithromycin should be provided.
  • When neither treatment is available, erythromycin 500 mg orally 4 times a day for 21 days is an alternative.
  • Doxycycline should not be used in pregnant women.

 

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Infectious Disease Society of America Guidelines on the Treatment of Lymphogranuloma Venereum

The Infectious Disease Society of America (IDSA) recommends doxycycline 100 mg orally twice daily for 21 days as first-line treatment.. [11]  No clinical studies currently support azithromycin for treatment.

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