Spontaneous Bacterial Peritonitis (SBP) Questions & Answers

Updated: Nov 26, 2018
  • Author: Thomas E Green, DO, MPH, MMM, CPE, FACEP, FACOEP; Chief Editor: Jeter (Jay) Pritchard Taylor, III, MD  more...
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Questions & Answers

Overview

What is spontaneous bacterial peritonitis (SBP)?

How does the presence of spontaneous bacterial peritonitis (SBP) affect the prognosis of patients with cirrhosis?

Which patients have an increased risk for developing spontaneous bacterial peritonitis (SBP)?

What is the pathophysiology of spontaneous bacterial peritonitis (SBP)?

What is the role of peritoneal inflammation in the pathophysiology of spontaneous bacterial peritonitis (SBP)?

Which organisms cause spontaneous bacterial peritonitis (SBP)?

What are the risk factors for spontaneous bacterial peritonitis (SBP)?

What is the prevalence of spontaneous bacterial peritonitis (SBP) in patients with ascites?

What are the race and sex predilections of spontaneous bacterial peritonitis (SBP)?

Which age groups are at highest risk for spontaneous bacterial peritonitis (SBP)?

What is the mortality rate of spontaneous bacterial peritonitis (SBP)?

Presentation

What are the signs and symptoms of spontaneous bacterial peritonitis (SBP)?

Which physical findings are characteristic of spontaneous bacterial peritonitis (SBP)?

DDX

Which conditions should be included in the differential diagnoses of spontaneous bacterial peritonitis (SBP)?

What are the differential diagnoses for Spontaneous Bacterial Peritonitis (SBP)?

Workup

What is the role of paracentesis in the evaluation of spontaneous bacterial peritonitis (SBP)?

What is the role of blood and urine cultures in the workup of spontaneous bacterial peritonitis (SBP)?

What is the role of imaging studies in the workup of spontaneous bacterial peritonitis (SBP)?

What is the indication for peritoneal fluid analysis in the workup of spontaneous bacterial peritonitis (SBP)?

What is the indication for ascitic fluid neutrophil count in the workup of spontaneous bacterial peritonitis (SBP)?

What is the role of ascitic fluid studies in the workup of spontaneous bacterial peritonitis (SBP)?

What subgroups are created from the results of the ascitic fluid polymorphonuclear neutrophil (PMN) count and the ascitic fluid culture in the workup of spontaneous bacterial peritonitis (SBP)?

Treatment

What are the treatment guidelines for spontaneous bacterial peritonitis (SBP)?

When is inpatient treatment indicated for spontaneous bacterial peritonitis (SBP)?

What is the role of probiotic therapy in the treatment of spontaneous bacterial peritonitis (SBP)?

What is the role of albumin infusion in the treatment of spontaneous bacterial peritonitis (SBP)?

What is included in inpatient care for spontaneous bacterial peritonitis (SBP)?

In which high risk patient groups is prophylaxis against spontaneous bacterial peritonitis (SBP) indicated?

What are possible adverse effects of prophylaxis for spontaneous bacterial peritonitis (SBP)?

Medications

What are the goals of drug treatment for spontaneous bacterial peritonitis (SBP)?

What is the efficacy of combination probiotic and antimicrobial therapy for spontaneous bacterial peritonitis (SBP)?

Which medications in the drug class Antimicrobials are used in the treatment of Spontaneous Bacterial Peritonitis (SBP)?