Pregnancy Trauma Medication

Updated: May 12, 2015
  • Author: Andrew K Chang, MD, MS; Chief Editor: Bruce M Lo, MD, MBA, CPE, RDMS, FACEP, FAAEM, FACHE  more...
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Medication

Medication Summary

The goal of therapy is to prevent immune response to Rh-negative fetus after trauma. RhoGAM (Rh immunoglobulin G) is administered for this purpose.

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Immune serum

Class Summary

Suppresses immune response of nonsensitized Rho(D)–negative mothers who are exposed to Rho(D)–positive blood from the fetus, resulting from a fetomaternal hemorrhage, abdominal trauma, amniocentesis, abortion, full-term delivery, or transfusion accident.

Rho(D) immune globulin (RhoGAM)

Administered if the patient is Rh-negative, unless the father also is Rh-negative. Suppresses the immune response of nonsensitized Rh-negative mothers after delivery of Rh-positive infant. Prevents sensitization to Rho(D) factor. Prevents erythroblastosis fetalis in subsequent pregnancy. When administered near the time of delivery, RhIgG may interfere with Rh typing of the newborn.

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