Hand-Foot-and-Mouth Disease in Emergency Medicine Follow-up

Updated: Oct 02, 2018
  • Author: Pamela L Dyne, MD; Chief Editor: Russell W Steele, MD  more...
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Inpatient & Outpatient Medications

Numerous potential remedies for the pain associated with the oral lesions (which may cause the child to decrease oral intake) in hand-foot-and-mouth (HFM) disease have been reported. These remedies have not been studied in any comparative or validated methodology; however, anecdotally they have been successful. These include the following:

  • "Magic mouthwash" consists of equal parts liquid Benadryl and Mylanta; mix and have the patient swish in the mouth and spit out.

  • The above is mixed with a crushed Carafate tablet; have the patient swish and spit out.



See the list below:

  • A secondary skin infection is the main complication.

  • These children can become dehydrated, resulting from decreased oral intake because of the discomfort of the oral lesions.

  • Rare neurologic and/or cardiopulmonary complications may occur. [17] These are usually associated with HEV71.



See the list below:

  • Patients have an excellent prognosis with full recovery anticipated.


Patient Education

See the list below:

  • Instruct patients' families regarding coxsackievirus contagion.

  • Instruct patients' families on home monitoring of hydration status and on warning signs of potentially complicating secondary skin infections.

  • The patient and family must be warned to minimize contact with the patient's oral and respiratory secretions for up to 2 weeks.

  • Good compulsive handwashing is important to minimize the spread of disease.

  • The virus may be present in the patient's feces for up to 1 month.