Pediatric Pyloric Stenosis Questions & Answers

1. Pandya S, Heiss K. Pyloric stenosis in pediatric surgery: an evidence-based review. Surg Clin North Am. 2012 Jun. 92(3):527-39, vii-viii. [QxMD MEDLINE Link].

2. Panteli C. New insights into the pathogenesis of infantile pyloric stenosis. Pediatr Surg Int. 2009 Sep 16. [QxMD MEDLINE Link].

3. Zhu J, Zhu T, Lin Z, Qu Y, Mu D. Perinatal risk factors for infantile hypertrophic pyloric stenosis: A meta-analysis. J Pediatr Surg. 2017 Sep. 52 (9):1389-1397. [QxMD MEDLINE Link].

4. McAteer JP, Ledbetter DJ, Goldin AB. Role of bottle feeding in the etiology of hypertrophic pyloric stenosis. JAMA Pediatr. 2013 Dec. 167(12):1143-9. [QxMD MEDLINE Link].

5. Lund M, Pasternak B, Davidsen RB, Feenstra B, Krogh C, Diaz LJ, et al. Use of macrolides in mother and child and risk of infantile hypertrophic pyloric stenosis: nationwide cohort study. BMJ. 2014 Mar 11. 348:g1908. [QxMD MEDLINE Link]. [Full Text].

6. Eberly MD, Eide MB, Thompson JL, Nylund CM. Azithromycin in early infancy and pyloric stenosis. Pediatrics. 2015 Mar. 135 (3):483-8. [QxMD MEDLINE Link].

7. Barclay L. Azithromycin Linked to Pyloric Stenosis Risk in Young Infants. Medscape Medical News. Available at http://www.medscape.com/viewarticle/839845. February 16, 2015; Accessed: July 28, 2015.

8. Murchison L, De Coppi P, Eaton S. Post-natal erythromycin exposure and risk of infantile hypertrophic pyloric stenosis: a systematic review and meta-analysis. Pediatr Surg Int. 2016 Dec. 32 (12):1147-1152. [QxMD MEDLINE Link].

9. Feenstra B, Geller F, Carstensen L, Romitti PA, Körberg IB, Bedell B, et al. Plasma lipids, genetic variants near APOA1, and the risk of infantile hypertrophic pyloric stenosis. JAMA. 2013 Aug 21. 310(7):714-21. [QxMD MEDLINE Link]. [Full Text].

10. Rogers IM. The true cause of pyloric stenosis is hyperacidity. Acta Paediatr. 2006 Feb. 95(2):132-6. [QxMD MEDLINE Link].

11. Krogh C, Fischer TK, Skotte L, Biggar RJ, Oyen N, Skytthe A. Familial aggregation and heritability of pyloric stenosis. JAMA. 2010 Jun 16. 303(23):2393-9. [QxMD MEDLINE Link].

12. [Guideline] Cincinnati Children's Hospital Medical Center. Evidence based clinical practice guideline for hypertrophic pyloric stenosis. Cincinnati (OH): Cincinnati Children's Hospital Medical Center; 2007 Nov 14. [Full Text].

13. Peters B, Oomen MW, Bakx R, Benninga MA. Advances in infantile hypertrophic pyloric stenosis. Expert Rev Gastroenterol Hepatol. 2014 Jul. 8 (5):533-41. [QxMD MEDLINE Link].

14. Maheshwari P, Abograra A, Shamam O. Sonographic evaluation of gastrointestinal obstruction in infants: a pictorial essay. J Pediatr Surg. 2009 Oct. 44(10):2037-42. [QxMD MEDLINE Link].

15. Sivitz AB, Tejani C, Cohen SG. Evaluation of hypertrophic pyloric stenosis by pediatric emergency physician sonography. Acad Emerg Med. 2013 Jul. 20 (7):646-51. [QxMD MEDLINE Link].

16. Mercer AE, Phillips R. Question 2: can a conservative approach to the treatment of hypertrophic pyloric stenosis with atropine be considered a real alternative to surgical pyloromyotomy?. Arch Dis Child. 2013 Jun. 98 (6):474-7. [QxMD MEDLINE Link].

17. Takeuchi M, Yasunaga H, Horiguchi H, Hashimoto H, Matsuda S. Pyloromyotomy versus i.v. atropine therapy for the treatment of infantile pyloric stenosis: nationwide hospital discharge database analysis. Pediatr Int. 2013 Aug. 55 (4):488-91. [QxMD MEDLINE Link].

18. Sola JE, Neville HL. Laparoscopic vs open pyloromyotomy: a systematic review and meta-analysis. J Pediatr Surg. 2009 Aug. 44 (8):1631-7. [QxMD MEDLINE Link].

19. Mahida JB, Asti L, Deans KJ, Minneci PC, Groner JI. Laparoscopic pyloromyotomy decreases postoperative length of stay in children with hypertrophic pyloric stenosis. J Pediatr Surg. 2016 Sep. 51 (9):1436-9. [QxMD MEDLINE Link].

20. Oomen MW, Hoekstra LT, Bakx R, Ubbink DT, Heij HA. Open versus laparoscopic pyloromyotomy for hypertrophic pyloric stenosis: a systematic review and meta-analysis focusing on major complications. Surg Endosc. 2012 Aug. 26 (8):2104-10. [QxMD MEDLINE Link].

21. Adibe OO, Nichol PF, Lim FY, Mattei P. Ad libitum feeds after laparoscopic pyloromyotomy: a retrospective comparison with a standardized feeding regimen in 227 infants. J Laparoendosc Adv Surg Tech A. 2007 Apr. 17(2):235-7. [QxMD MEDLINE Link].

22. Kelley-Quon LI, Tseng CH, Jen HC, Shew SB. Hospital type predicts surgical complications for infants with hypertrophic pyloric stenosis. Am Surg. 2012 Oct. 78(10):1079-82. [QxMD MEDLINE Link].

23. Binet A, Klipfel C, Meignan P, Bastard F, Cook AR, Braïk K, et al. Laparoscopic pyloromyotomy for hypertrophic pyloric stenosis: a survey of 407 children. Pediatr Surg Int. 2018 Apr. 34 (4):421-426. [QxMD MEDLINE Link].

24. Lauriti G, Cascini V, Chiesa PL, Pierro A, Zani A. Atropine Treatment for Hypertrophic Pyloric Stenosis: A Systematic Review and Meta-Analysis. Eur J Pediatr Surg. 2018 Oct. 28 (5):393-399. [QxMD MEDLINE Link].

Sathyaseelan Subramaniam, MD, FAAP Chief Fellow in Pediatric Emergency Medicine, Kings County Hospital, State University of New York Downstate Medical Center

Sathyaseelan Subramaniam, MD, FAAP is a member of the following medical societies: American Academy of Emergency Medicine, American Academy of Pediatrics, American Institute of Ultrasound in Medicine

Disclosure: Nothing to disclose.

Jennifer H Chao, MD, FAAP Clinical Associate Professor of Pediatric Emergency Medicine, State University of New York Downstate College of Medicine; Attending Physician, Pediatric Emergency Department, Kings County Hospital and University Hospital Brooklyn

Jennifer H Chao, MD, FAAP is a member of the following medical societies: American Academy of Pediatrics, American College of Emergency Physicians

Disclosure: Nothing to disclose.

Richard H Sinert, DO Professor of Emergency Medicine, Clinical Assistant Professor of Medicine, Research Director, State University of New York College of Medicine; Consulting Staff, Vice-Chair in Charge of Research, Department of Emergency Medicine, Kings County Hospital Center

Richard H Sinert, DO is a member of the following medical societies: American College of Physicians, Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

Mary L Windle, PharmD Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Nothing to disclose.

Grace M Young, MD Associate Professor, Department of Pediatrics, University of Maryland Medical Center

Grace M Young, MD is a member of the following medical societies: American Academy of Pediatrics, American College of Emergency Physicians

Disclosure: Nothing to disclose.

Kirsten A Bechtel, MD Associate Professor of Pediatrics, Section of Pediatric Emergency Medicine, Yale University School of Medicine; Co-Director, Injury Free Coalition for Kids, Yale-New Haven Children's Hospital

Kirsten A Bechtel, MD is a member of the following medical societies: American Academy of Pediatrics

Disclosure: Nothing to disclose.

Garry Wilkes, MBBS, FACEM Emergency Physician, Echuca Regional Health, Victoria; Clinical Associate Professor, University of Western Australia, Australia

Disclosure: Nothing to disclose.

Jagvir Singh, MD Director, Division of Pediatric Emergency Medicine, Lutheran General Hospital of Park Ridge

Jagvir Singh, MD is a member of the following medical societies: American Academy of Pediatrics

Disclosure: Nothing to disclose.

Dara A Kass, MD Clinical Assistant Instructor, Department of Emergency Medicine, State University of New York Downstate Medical Center, Kings County Hospital

Dara A Kass, MD is a member of the following medical societies: American College of Emergency Physicians, Emergency Medicine Residents Association, and Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

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