Antidepressant Toxicity Follow-up

Updated: Apr 12, 2015
  • Author: Jeena Jacob, MD, PharmD; Chief Editor: Asim Tarabar, MD  more...
  • Print
Follow-up

Further Inpatient Care

See the list below:

  • Patients being treated for antidepressant toxicity may need repeat boluses of bicarbonate and may require cardiac monitoring and ICU care if admitted.
Next:

Complications

Complications of antidepressant toxicity may include the following:

  • CNS sequelae
  • Seizures
  • Dysrhythmias
  • Hypotension
Previous
Next:

Prognosis

See the list below:

  • Prognosis is generally favorable without long-term CNS or cardiovascular sequelae in patients who survive initial toxicity. Patients show clinical signs of toxicity in the first 6 hours; survival beyond this time suggests a favorable prognosis unless severe hypoxia or hypotension were present before initial treatment.
  • A small subset may have prolonged neurologic sequelae after status seizures or persistent hypotension.
  • Patients who remain asymptomatic without medical intervention following 6 hours of emergency department observation receive GI decontamination and have normal EKG findings with normal QRS duration may be medically cleared.
Previous
Next:

Patient Education

See the list below:

Previous