Carbamazepine Toxicity Questions & Answers

Updated: Apr 29, 2020
  • Author: Muhammad Waseem, MS, MBBS, FAAP, FACEP, FAHA; Chief Editor: Stephen L Thornton, MD  more...
  • Print
Questions & Answers

Overview

What is carbamazepine toxicity?

What is the pathophysiology of carbamazepine toxicity?

What causes carbamazepine toxicity?

What is the prevalence of carbamazepine toxicity?

Which age groups are at highest risk for carbamazepine toxicity?

Which patient groups are at increased risk for carbamazepine-induced Stevens-Johnson syndrome?

What is the prognosis carbamazepine toxicity?

What is included in patient education about carbamazepine toxicity?

Presentation

What is the focus of clinical history in cases of suspected carbamazepine toxicity?

What are the signs and symptoms of carbamazepine toxicity?

Which ingestion history findings are characteristic of carbamazepine toxicity?

Which vital sign findings are characteristic of carbamazepine toxicity?

Which neurologic findings are characteristic of carbamazepine toxicity?

Which respiratory findings are characteristic of carbamazepine toxicity?

Which cardiovascular findings are characteristic of carbamazepine toxicity?

Which GI findings are characteristic of carbamazepine toxicity?

Which hematologic findings are characteristic of carbamazepine toxicity?

Which dermatologic findings are characteristic of carbamazepine toxicity?

Which endocrine findings are characteristic of carbamazepine toxicity?

What are the risk factors for carbamazepine toxicity-related hyponatremia?

What causes carbamazepine toxicity-related death?

DDX

Which conditions are included in the differential diagnoses of carbamazepine toxicity?

Which conditions are included in the differential diagnoses of carbamazepine toxicity-related coma?

Which conditions are included in the differential diagnoses of carbamazepine toxicity-related arrhythmias?

Which conditions are included in the differential diagnoses of carbamazepine toxicity-related seizures?

What are the differential diagnoses for Carbamazepine Toxicity?

Workup

What is the role of lab tests in the workup of carbamazepine toxicity?

What is the role of imaging studies in the workup of carbamazepine toxicity?

What is the role of ECG in the workup of carbamazepine toxicity?

What is the role of hair analysis in the workup of carbamazepine toxicity?

Treatment

What is included in prehospital care for carbamazepine toxicity?

What is included in emergency department care for carbamazepine toxicity?

What are the discharge criteria following emergency treatment of carbamazepine toxicity?

What is the role of activated charcoal and lavage in the treatment of carbamazepine toxicity?

What is the role of whole bowel irrigation in the treatment of carbamazepine toxicity?

What is the role of charcoal hemoperfusion in the treatment of carbamazepine toxicity?

What is the role of dialysis in the treatment of carbamazepine toxicity?

Which specialist consultations are beneficial to patients with carbamazepine toxicity?

What is included in the long-term monitoring following carbamazepine toxicity?

Guidelines

What are the Extracorporeal Treatments in Poisoning (EXTRIP) treatment guidelines for carbamazepine toxicity?

Medications

What is the role of medications in the treatment of carbamazepine toxicity?

Which medications in the drug class Cathartic are used in the treatment of Carbamazepine Toxicity?

Which medications in the drug class Alkalinizing Agent are used in the treatment of Carbamazepine Toxicity?

Which medications in the drug class Benzodiazepines are used in the treatment of Carbamazepine Toxicity?

Which medications in the drug class Antidote, Adsorbent are used in the treatment of Carbamazepine Toxicity?