Chirica M, Bonavina L, Kelly MD, Sarfati E, Cattan P. Caustic ingestion. Lancet. 2017 May 20. 389 (10083):2041-2052. [QxMD MEDLINE Link].
Gummin DD, Mowry JB, Beuhler MC, Spyker DA, Bronstein AC, Rivers LJ, et al. 2020 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 38th Annual Report. Clin Toxicol (Phila). 2021 Dec. 59 (12):1282-1501. [QxMD MEDLINE Link]. [Full Text].
Kurowski JA, Kay M. Caustic Ingestions and Foreign Bodies Ingestions in Pediatric Patients. Pediatr Clin North Am. 2017 Jun. 64 (3):507-524. [QxMD MEDLINE Link].
Denney W, Ahmad N, Dillard B, Nowicki MJ. Children will eat the strangest things: a 10-year retrospective analysis of foreign body and caustic ingestions from a single academic center. Pediatr Emerg Care. 2012 Aug. 28(8):731-4. [QxMD MEDLINE Link].
Elshabrawi M, A-Kader HH. Caustic ingestion in children. Expert Rev Gastroenterol Hepatol. 2011 Oct. 5(5):637-45. [QxMD MEDLINE Link].
Chang JM, Liu NJ, Pai BC, Liu YH, Tsai MH, Lee CS, et al. The role of age in predicting the outcome of caustic ingestion in adults: a retrospective analysis. BMC Gastroenterol. 2011 Jun 14. 11:72. [QxMD MEDLINE Link]. [Full Text].
Chen YJ, Seak CJ, Chen CC, Chen TH, Kang SC, Ng CJ, et al. The Association Between Caustic Ingestion and Psychiatric Comorbidity Based on 396 Adults Within 20 Years. Risk Manag Healthc Policy. 2020. 13:1815-1824. [QxMD MEDLINE Link]. [Full Text].
Rollin M, Jaulim A, Vaz F, Sandhu G, Wood S, Birchall M, et al. Caustic ingestion injury of the upper aerodigestive tract in adults. Ann R Coll Surg Engl. 2015 May. 97 (4):304-7. [QxMD MEDLINE Link]. [Full Text].
Riffat F, Cheng A. Pediatric caustic ingestion: 50 consecutive cases and a review of the literature. Dis Esophagus. 2009. 22(1):89-94. [QxMD MEDLINE Link].
Bruzzi M, Chirica M, Resche-Rigon M, Corte H, Voron T, Sarfati E, et al. Emergency Computed Tomography Predicts Caustic Esophageal Stricture Formation. Ann Surg. 2018 Mar 12. 22 (10):1659-1664. [QxMD MEDLINE Link].
Lurie Y, Slotky M, Fischer D, Shreter R, Bentur Y. The role of chest and abdominal computed tomography in assessing the severity of acute corrosive ingestion. Clin Toxicol (Phila). 2013 Nov. 51(9):834-7. [QxMD MEDLINE Link].
Kamijo Y, Kondo I, Watanabe M, Kan'o T, Ide A, Soma K. Gastric stenosis in severe corrosive gastritis: prognostic evaluation by endoscopic ultrasonography. Clin Toxicol. 2007. 45(3):284-6. [QxMD MEDLINE Link].
Hoffman RS, Burns MM, Gosselin S. Ingestion of Caustic Substances. N Engl J Med. 2020 Apr 30. 382(18):1739-1748. [QxMD MEDLINE Link].
Zargar SA, Kochhar R, Mehta S, Mehta SK. The role of fiberoptic endoscopy in the management of corrosive ingestion and modified endoscopic classification of burns. Gastrointest Endosc. 1991 Mar-Apr. 37 (2):165-9. [QxMD MEDLINE Link].
Bird JH, Kumar S, Paul C, Ramsden JD. Controversies in the management of caustic ingestion injury: an evidence-based review. Clin Otolaryngol. 2017 Jun. 42 (3):701-708. [QxMD MEDLINE Link].
Arnold M, Numanoglu A. Caustic ingestion in children-A review. Semin Pediatr Surg. 2017 Apr. 26 (2):95-104. [QxMD MEDLINE Link].
Contini S, Scarpignato C. Caustic injury of the upper gastrointestinal tract: a comprehensive review. World J Gastroenterol. 2013 Jul 7. 19 (25):3918-30. [QxMD MEDLINE Link]. [Full Text].
Bird JH, Kumar S, Paul C, Ramsden JD. Controversies in the management of caustic ingestion injury: an evidence-based review. Clin Otolaryngol. 2017 Jun. 42 (3):701-708. [QxMD MEDLINE Link].
Anderson KD, Rouse TM, Randolph JG. A controlled trial of corticosteroids in children with corrosive injury of the esophagus. N Engl J Med. 1990 Sep 6. 323(10):637-40. [QxMD MEDLINE Link].
Fulton JA, Hoffman RS. Steroids in second degree caustic burns of the esophagus: a systematic pooled analysis of fifty years of human data: 1956-2006. Clin Toxicol. 2007 May. 45(4):402-8. [QxMD MEDLINE Link].
Usta M, et al. High doses of methylprednisolone in the management of caustic esophageal burns. Pediatrics. 2014 Jun. 133(6):E1518-24. [QxMD MEDLINE Link].
Uygun I, Arslan MS, Aydogdu B, Okur MH, Otcu S. Fluoroscopic balloon dilatation for caustic esophageal stricture in children: an 8-year experience. J Pediatr Surg. 2013 Nov. 48(11):2230-4. [QxMD MEDLINE Link].
[Guideline] Tringali A, Thomson M, Dumonceau JM, Tavares M, Tabbers MM, et al. Pediatric gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) and European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) Guideline Executive summary. Endoscopy. 2017 Jan. 49 (1):83-91. [QxMD MEDLINE Link]. [Full Text].
Katibe R, Abdelgadir I, McGrogan P, Akobeng AK. Corticosteroids for Preventing Caustic Esophageal Strictures: Systematic Review and Meta-analysis. J Pediatr Gastroenterol Nutr. 2018 Jun. 66 (6):898-902. [QxMD MEDLINE Link].

Media Gallery

Caustic ingestions. Endoscopic view of the esophagus in a patient who ingested hydrochloric acid (Lime-a-way). Note the extensive thrombosis of the esophageal submucosal vessels giving the appearance similar to chicken wire. Courtesy of Ferdinando L Mirarchi, DO, Fred P Harchelroad, Jr, MD, Sangeeta Gulati, MD, and George J Brodmerkel, Jr, MD.
Caustic ingestions. Endoscopic view of the esophagus in a patient who ingested hydrochloric acid (Lime-a-way). Note the appearance of the thrombosed esophageal submucosal vessels giving the appearance of chicken wire. Courtesy of Ferdinando L Mirarchi, DO, Fred P Harchelroad, Jr, MD, Sangeeta Gulati, MD, and George J Brodmerkel, Jr, MD.
Caustic ingestions. Endoscopic view of the esophagus in a patient who ingested hydrochloric acid (Lime-a-way). Note the extensive burn and thrombosis of the submucosal esophageal vessels, which gives the appearance of chicken wire. Courtesy of Ferdinando L Mirarchi, DO, Fred P Harchelroad, Jr, MD, Sangeeta Gulati, MD, and George J Brodmerkel, Jr, MD.

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Classification of caustic mucosal damage^[14]

Classification of caustic mucosal damage ^[14]

Grade	Findings	Complication risk
0	None	None
1	Swelling and redness of mucosa	Low risk for development of outlet obstruction of strictures
2A	Superficial ulcers, bleeding, friability	Low risk for development of outlet obstruction of strictures
2B	Deep ulcers, bleeding, friability	High risk for strictures, low risk for perforation
3A	Focal necrosis	High risk for strictures, moderate risk for perforation
3B	Extensive necrosis	High risk for strictures and perforation, moderate risk for fatality
4	Perforation	High risk of fatality

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