Medication-Induced Dystonic Reactions Follow-up

Updated: Jun 29, 2016
  • Author: John Michael Kowalski, DO; Chief Editor: Asim Tarabar, MD  more...
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Follow-up

Further Outpatient Care

Consider discontinuing the inciting agent.

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Further Inpatient Care

In cases with respiratory compromise, as with laryngeal involvement, patients should be observed for a prolonged period (12-24 h). [21]

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Inpatient & Outpatient Medications

Continue medication for 48-72 hours to prevent relapse, as follows:

  • Benztropine 1-2 mg PO bid
  • Diphenhydramine 25-50 mg PO qid
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Prognosis

Complete resolution of symptoms is expected following treatment. However, symptoms may reoccur up to 72 hours later. No long-term sequelae are expected from acute dystonic reactions once the inciting agent is discontinued.

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