Overview
What is ethylene glycol (EG) toxicity?
What are stages of ethylene glycol (EG) toxicity?
What is the pathophysiology of ethylene glycol (EG) toxicity?
What is the incidence of ethylene glycol (EG) toxicity in the US?
Presentation
What should be the focus of clinical history for suspected ethylene glycol (EG) toxicity?
Which physical findings suggest ethylene glycol (EG) toxicity?
What causes ethylene glycol (EG) toxicity?
DDX
Which conditions should be included in the differential diagnoses of ethylene glycol (EG) toxicity?
What are the differential diagnoses for Ethylene Glycol Toxicity?
Workup
What is the role of lab testing in the diagnosis of ethylene glycol (EG) toxicity?
What is the role of serum osmolality in the diagnosis of ethylene glycol (EG) toxicity?
Which lab tests should be performed in symptomatic patients with ethylene glycol (EG) toxicity?
What is the role of a Wood's lamp in the diagnosis of ethylene glycol (EG) toxicity?
What is the role of imaging studies in the diagnosis of ethylene glycol (EG) toxicity?
What is the role of urine microscopy in the diagnosis of ethylene glycol (EG) toxicity?
Treatment
What is the initial emergency department (ED) treatment of ethylene glycol (EG) toxicity?
What is included in prehospital care for ethylene glycol (EG) toxicity?
When is treatment for suspected ethylene glycol (EG) intoxication indicated?
What is the role of fomepizole (Antizol) in the treatment of ethylene glycol (EG) toxicity?
What is the role of ethanol in the treatment of ethylene glycol (EG) toxicity?
What is the role of hemodialysis in the treatment of ethylene glycol (EG) toxicity?
Which specialist consultations are beneficial to patients with ethylene glycol (EG) toxicity?
Medications
Which medications are used in the treatment of ethylene glycol (EG) toxicity?
Which medications in the drug class Nutrients are used in the treatment of Ethylene Glycol Toxicity?
Which medications in the drug class Antidotes are used in the treatment of Ethylene Glycol Toxicity?
-
Oxalate crystals. Courtesy of John D Schaldenbrand, MD, Department of Pathology, St Joseph Mercy Health System, Ann Arbor, MI.
-
Ethylene glycol.