Tropane Alkaloid Poisoning Workup

Updated: Dec 06, 2015
  • Author: Richard A Wagner, MD, PhD, FACEP, FAAEM; Chief Editor: Asim Tarabar, MD  more...
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Workup

Laboratory Studies

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  • No specific diagnostic studies for tropane alkaloid poisonings exist.
  • Tropane alkaloids are not included in standard drugs of abuse or comprehensive toxicology panels; serum drug concentrations are neither helpful nor readily available to aid in initial management.
  • Since acetaminophen and salicylate are common co-ingestants in many poisonings, consider assays for acetaminophen and salicylate levels.
  • In febrile patients, consider blood and urine cultures.
  • Serum electrolyte levels may provide insight into other intoxicating agents and co-ingestants.
  • Consider a pregnancy test for all patients capable of bearing children.
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Imaging Studies

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  • Consider CT scan of the head for patients with altered mental status that is inadequately explained by toxicity from ingested agent or is unresponsive to appropriate intervention.
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Other Tests

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  • Obtain an electrocardiogram (ECG) at presentation for all patients with suspected toxic ingestions.
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Procedures

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  • Consider lumbar puncture (LP) for patients with fever and altered mental status.
  • Consider invasive monitoring for hemodynamically unstable patients.
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