Orellanine Mushroom Toxicity Follow-up

Updated: Aug 21, 2014
  • Author: Reed Brozen, MD; Chief Editor: Asim Tarabar, MD  more...
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Follow-up

Further Outpatient Care

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  • Early management of an orellanine exposure without signs of renal injury is undefined. Consider outpatient management only after careful consultation with a toxicologist and/or nephrologist and if close follow-up is possible.
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Further Inpatient Care

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  • Admit all symptomatic patients for further management and observation.
  • Intermittent hemodialysis may be necessary if renal failure is severe.
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Transfer

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  • Patient should be in a facility that has nephrology specialists and hemodialysis capability.
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Deterrence/Prevention

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  • General education regarding dangers of foraging for and ingesting unknown mushrooms is important.
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Prognosis

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  • Short latent period before onset of illness and renal injury portents more severe renal insult and prolonged period of renal failure than delayed onset of illness.
  • Relatively mild degrees of renal insufficiency may resolve within weeks to months. Some may be treated expectantly without need for hemodialysis. In more severe cases, renal failure can persist months to years requiring chronic hemodialysis or renal transplant.
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Patient Education

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