Sedative-Hypnotic Toxicity Follow-up

Updated: Dec 29, 2015
  • Author: Jeffrey S Cooper, MD, FAAEM, FACEP; Chief Editor: Asim Tarabar, MD  more...
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Follow-up

Further Inpatient Care

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  • Assess for suicide risk.
  • With barbiturate toxicity, patients may be discharged after 6 hours of observation, provided that they are asymptomatic or minimally symptomatic.
  • Observe patients with benzodiazepine toxicity for at least 2 hours after recovery from flumazenil for late respiratory depression or resedation.
  • Patients with glutethimide (Doriden) toxicity require 24 hours of observation in the hospital.
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Complications

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  • Some sedative-hypnotics may have teratogenic or mutagenic effects.
  • Complications associated with mortality in patients requiring intubation include difficulties with intubation, shock, and evidence of gastric aspiration. [6]
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Patient Education

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