Thyroid Hormone Toxicity Workup

Updated: Oct 12, 2016
  • Author: Lisandro Irizarry, MD, MPH, FACEP; Chief Editor: Asim Tarabar, MD  more...
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Workup

Laboratory Studies

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  • Most asymptomatic patients do not require diagnostic testing, especially very early after exposure.

  • The following tests are indicated in symptomatic patients:

    • Complete blood count

    • Electrolytes (eg, calcium, magnesium, phosphorous)

    • Urinalysis

    • Serum acetaminophen level (in patients with intentional exposures and suicidal ideations)

    • Arterial blood gas (ABG)

    • T3, T4, and T3 resin uptake (RU) levels may be sent 2-6 hours postingestion; however, remember the following:

      • These levels offer no aid in the acute phase of clinical management.

      • These levels are of no value in determining prognosis.

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Other Tests

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Procedures

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  • Lumbar puncture (LP) should be considered in patients with hyperthermia and change of mental status to rule out CNS infection.

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