Thallium Toxicity Medication

Updated: Feb 19, 2018
  • Author: Chip Gresham, MD, FACEM; Chief Editor: David Vearrier, MD, MPH  more...
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Medication

Medication Summary

Institute treatment of thallium intoxication as soon as the diagnosis is suspected because tissue-bound thallium may cause prolonged neurologic damage if detoxification therapy is not commenced within 72 h of onset of acute poisoning.

 

 

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GI decontaminants

Class Summary

These agents bind thallium in the GI tract and prevent enterohepatic recirculation.

Prussian blue (Antidotum Thallii-Heyl, Radiogardase-Cs)

Mixture of several ferrocyanic complexes, mainly KFe(III)Fe(II)(CN)6 (Turnbull Blue) and the reverse complex (hexacyanoferrate). Used as a pigment in paint and ink manufacturing. DOC for thallium poisoning.

Activated charcoal (Liqui-Char)

Emergency treatment in poisoning caused by drugs and chemicals; network of pores present in activated charcoal adsorbs 100-1000 mg of drug per gram of charcoal; does not dissolve in water; for maximum effect, administer within 30 min of poison ingestion.

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