Overview
What are selective serotonin reuptake inhibitors (SSRIs)?
What is serotonin syndrome (SS)?
What causes serotonin reuptake inhibitor (SSRI) toxicity?
What are the causes of serotonin syndrome (SS)?
What is the role of trazodone in the etiology of serotonin syndrome (SS)?
What is the role of bupropion (Wellbutrin) in the etiology of serotonin syndrome (SS)?
Which opioids are associated with serotonin syndrome (SS)?
Which antimicrobial agents are associated with serotonin syndrome (SS)?
What is the pharmacokinetics of selective serotonin reuptake inhibitor (SSRI) toxicity?
What are the complications of selective serotonin reuptake inhibitor (SSRI) toxicity?
What causes serotonin syndrome (SS)?
What are the physiologic manifestations of serotonin syndrome (SS)?
What are the GI effects of selective serotonin reuptake inhibitor (SSRI) toxicity?
What is the incidence of selective serotonin reuptake inhibitor (SSRI) toxicity in the US?
How does the incidence of selective serotonin reuptake inhibitor (SSRI) toxicity vary by age?
What is the prognosis of selective serotonin reuptake inhibitor (SSRI) toxicity?
What causes fatality in selective serotonin reuptake inhibitor (SSRI) toxicity?
Presentation
When is selective serotonin reuptake inhibitor toxicity most likely to develop?
What are the diagnostic criteria for serotonin syndrome (SS)?
What are the signs and symptoms of serotonin syndrome (SS)?
DDX
What are the differential diagnoses for Selective Serotonin Reuptake Inhibitor Toxicity?
Workup
Which procedures are used in the workup of selective serotonin reuptake inhibitor (SSRI) toxicity?
Treatment
What are the treatment options for selective serotonin reuptake inhibitor (SSRI) toxicity?
What is included in inpatient care for selective serotonin reuptake inhibitor (SSRI) toxicity?
How is symptomatic citalopram/escitalopram overdose managed?
What is included in prehospital care for selective serotonin reuptake inhibitor (SSRI) toxicity?
How is severe hyperthermia in selective serotonin reuptake inhibitor (SSRI) toxicity managed?
How is selective serotonin reuptake inhibitor (SSRI) toxicity prevented when switching medications?
Medications