3-Quinuclidinyl Benzilate Poisoning Differential Diagnoses

Updated: Feb 22, 2021
  • Author: Christopher P Holstege, MD; Chief Editor: Duane C Caneva, MD, MSc  more...
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DDx

Diagnostic Considerations

Other problems to be considered in the differential diagnosis include the following:

  • Thyrotoxicosis

  • Neuroleptic malignant syndrome

  • Serotonin syndrome

  • CNS infection

  • Heat-related illness (e.g., heat stroke)

  • Sedative-hypnotic withdrawal

  • Hallucinogenic indolealkylamines, which are unique analogues of 5-hydroxytryptamine (eg, the psilocybin-containing mushrooms, ibogaine, bufotenine, dimethyltryptamine, lysergic acid). [3]   

  • Anxiety - An important, sometimes overlooked cause of similar symptoms, which can manifest with such findings as dizziness, tachycardia, sweating, headache, and even loss of sensation or ability to move parts of the body. This cause is a diagnosis of exclusion. [3]

  • Anticholinergic "outbreaks" from other substances, such as from specific plants (eg, Datura stramonium) and numeorus pharmaceuticals (eg, diphenhydramine, scopolamine, atropine). [4]

Differential Diagnoses