Distraction Osteogenesis of the Mandible Workup

1. Ilizarov GA, Ledyaev VI. The replacement of long tubular bone defects by lengthening distraction osteotomy of one of the fragments. 1969. Clin Orthop Relat Res. 1992 Jul. 7-10. [Medline].

2. McCarthy JG, Schreiber J, Karp N, Thorne CH, Grayson BH. Lengthening the human mandible by gradual distraction. Plast Reconstr Surg. 1992 Jan. 89(1):1-8; discussion 9-10. [Medline].

3. Tibesar RJ, Price DL, Moore EJ. Mandibular distraction osteogenesis to relieve Pierre Robin airway obstruction. Am J Otolaryngol. 2006 Nov-Dec. 27(6):436-9. [Medline].

4. González-García R, Naval-Gías L, Rodríguez-Campo FJ. Distraction osteogenesis in the irradiated mandible for segmental mandibular reconstruction. J Oral Maxillofac Surg. 2009 Jul. 67(7):1573-4. [Medline].

5. Meyer U, Kruse-Lösler B, Wiesmann HP. Principles of bone formation driven by biophysical forces in craniofacial surgery. Br J Oral Maxillofac Surg. 2006 Aug. 44(4):289-95. [Medline].

6. Hong P, Boyd D, Beyea SD, Bezuhly M. Enhancement of bone consolidation in mandibular distraction osteogenesis: a contemporary review of experimental studies involving adjuvant therapies. J Plast Reconstr Aesthet Surg. 2013 Jul. 66(7):883-95. [Medline].

7. Hong P. A clinical narrative review of mandibular distraction osteogenesis in neonates with Pierre Robin sequence. Int J Pediatr Otorhinolaryngol. 2011 Aug. 75(8):985-91. [Medline].

8. Saulacic N, Zix J, Iizuka T. Complication rates and associated factors in alveolar distraction osteogenesis: a comprehensive review. Int J Oral Maxillofac Surg. 2009 Mar. 38(3):210-7. [Medline].

9. Hwang SJ, Jung JG, Jung JU, Kyung SH. Vertical alveolar bone distraction at molar region using lag screw principle. J Oral Maxillofac Surg. 2004 Jul. 62(7):787-94. [Medline].

10. Rachmiel A, Srouji S, Peled M. Alveolar ridge augmentation by distraction osteogenesis. Int J Oral Maxillofac Surg. 2001 Dec. 30(6):510-7. [Medline].

11. Clark CL, Strider J, Hall C, Ferguson HW, Armstrong KL, Runner RR. Distraction osteogenesis in irradiated rabbit mandibles with adjunctive hyperbaric oxygen therapy. J Oral Maxillofac Surg. 2006 Apr. 64(4):589-93. [Medline].

12. Costantino PD, Friedman CD. Distraction osteogenesis. Applications for mandibular regrowth. Otolaryngol Clin North Am. 1991 Dec. 24(6):1433-43. [Medline].

13. Pereira MA, Luiz de Freitas PH, da Rosa TF, Xavier CB. Understanding distraction osteogenesis on the maxillofacial complex: a literature review. J Oral Maxillofac Surg. 2007 Dec. 65(12):2518-23. [Medline].

14. Cho BC, Kim JY, Lee JH, Chung HY, Park JW, Roh KH. The bone regenerative effect of chitosan microsphere-encapsulated growth hormone on bony consolidation in mandibular distraction osteogenesis in a dog model. J Craniofac Surg. 2004 Mar. 15(2):299-311; discussion 312-3. [Medline].

15. Ashinoff RL, Cetrulo CL Jr, Galiano RD, Dobryansky M, Bhatt KA, Ceradini DJ. Bone morphogenic protein-2 gene therapy for mandibular distraction osteogenesis. Ann Plast Surg. 2004 Jun. 52(6):585-90; discussion 591. [Medline].

16. Freddo AL, Hübler R, de Castro-Beck CA, Heitz C, de Oliveira MG. A preliminary study of hardness and modulus of elasticity in sheep mandibles submitted to distraction osteogenesis and low-level laser therapy. Med Oral Patol Oral Cir Bucal. 2012 Jan. 17(1):e102-7. [Medline].

17. Kreisner PE, Blaya DS, Gaião L, Maciel-Santos ME, Etges A, Santana-Filho M. Histological evaluation of the effect of low-level laser on distraction osteogenesis in rabbit mandibles. Med Oral Patol Oral Cir Bucal. 2010 Jul. 15(4):e616-8. [Medline].

18. Chiapasco M, Consolo U, Bianchi A, Ronchi P. Alveolar distraction osteogenesis for the correction of vertically deficient edentulous ridges: a multicenter prospective study on humans. Int J Oral Maxillofac Implants. 2004 May-Jun. 19(3):399-407. [Medline].

19. Robiony M, Toro C, Stucki-McCormick SU, Zerman N, Costa F, Politi M. The "FAD" (Floating Alveolar Device): a bidirectional distraction system for distraction osteogenesis of the alveolar process. J Oral Maxillofac Surg. 2004 Sep. 62(9 Suppl 2):136-42. [Medline].

20. Mazzonetto R, Allais M, Maurette PE, Moreira RW. A retrospective study of the potential complications during alveolar distraction osteogenesis in 55 patients. Int J Oral Maxillofac Surg. 2007 Jan. 36(1):6-10. [Medline].

21. Zheng LW, Wong MC, Rabie AB, Cheung LK. Evaluation of recombinant human bone morphogenetic protein-2 in mandibular distraction osteogenesis in rabbits: Effect of dosage and number of doses on formation of bone. Br J Oral Maxillofac Surg. 2006 Dec. 44(6):487-94. [Medline].

22. Kim IS, Park JW, Kwon IC, Baik BS, Cho BC. Role of BMP, betaig-h3, and chitosan in early bony consolidation in distraction osteogenesis in a dog model. Plast Reconstr Surg. 2002 May. 109(6):1966-77. [Medline].

23. Jiang X, Zou S, Ye B, Zhu S, Liu Y, Hu J. bFGF-Modified BMMSCs enhance bone regeneration following distraction osteogenesis in rabbits. Bone. 2010 Apr. 46(4):1156-61. [Medline].

24. Cho BC, Moon JH, Chung HY, Park JW, Kweon IC, Kim IS. The bone regenerative effect of growth hormone on consolidation in mandibular distraction osteogenesis of a dog model. J Craniofac Surg. 2003 May. 14(3):417-25. [Medline].

25. Gateno J, Seymour-Dempsey K, Teichgraeber JF, Lalani Z, Yanez R, Xia JJ. Prototype testing for a new bioabsorbable Le Fort III distraction device: a pilot study. J Oral Maxillofac Surg. 2004 Dec. 62(12):1517-23. [Medline].

26. Cohen SR, Holmes RE. Internal Le Fort III distraction with biodegradable devices. J Craniofac Surg. 2001 May. 12(3):264-72. [Medline].

27. Goldwaser BR, Magill J, Papadaki ME, Byl M, Kromann R, Yates B. Continuous mandibular distraction osteogenesis: novel device and preliminary results in minipigs. J Oral Maxillofac Surg. 2013 Apr. 71(4):e168-77. [Medline].

28. Peacock ZS, Tricomi BJ, Murphy BA, Magill JC, Kaban LB, Troulis MJ. Automated continuous distraction osteogenesis may allow faster distraction rates: a preliminary study. J Oral Maxillofac Surg. 2013 Jun. 71(6):1073-84. [Medline].

29. Alkan A, Ozer M, Bas B, Bayram M, Celebi N, Inal S. Mandibular symphyseal distraction osteogenesis: review of three techniques. Int J Oral Maxillofac Surg. 2007 Feb. 36(2):111-7. [Medline].

30. Azumi Y, Sugawara J, Takahashi I, Mitani H, Nagasaka H, Kawamura H. Positional and morphologic changes of the mandibular condyle after mandibular distraction osteogenesis in skeletal class II patients. World J Orthod. 2004 Spring. 5(1):32-9. [Medline].

31. Block MS, Brister GD. Use of distraction osteogenesis for maxillary advancement: preliminary results. J Oral Maxillofac Surg. 1994 Mar. 52(3):282-6; discussion 287-8. [Medline].

32. Breuning KH, van Strijen PJ, Prahl-Andersen B, Tuinzing DB. Duration of orthodontic treatment and mandibular lengthening by means of distraction or bilateral sagittal split osteotomy in patients with Angle Class II malocclusions. Am J Orthod Dentofacial Orthop. 2005 Jan. 127(1):25-9. [Medline].

33. Chin M, Toth BA. Distraction osteogenesis in maxillofacial surgery using internal devices: review of five cases. J Oral Maxillofac Surg. 1996 Jan. 54(1):45-53; discussion 54. [Medline].

34. Clark CL, Strider J, Hall C, Ferguson HW, Armstrong KL, Runner RR, et al. Distraction osteogenesis in irradiated rabbit mandibles with adjunctive hyperbaric oxygen therapy. J Oral Maxillofac Surg. 2006 Apr. 64(4):589-93. [Medline].

35. Delloye C, Delefortrie G, Coutelier L, Vincent A. Bone regenerate formation in cortical bone during distraction lengthening. An experimental study. Clin Orthop Rel Res. 1990. 250: 34-42.

36. Douglas P. Sinn, DDS, Wichit Taranon, DDS. Three-Dimensional Planning for Mandibular Distraction Osteogenesis in Hemifacial Microsomia Patients: Prediction Tracing and Results. [Full Text].

37. Eski M, Turegun M, Deveci M, Gokce HS, Sengezer M. Vertical distraction osteogenesis of fibular bone flap in reconstructed mandible. Ann Plast Surg. 2006 Dec. 57(6):631-6. [Medline].

38. Fritz MA, Sidman JD. Distraction osteogenesis of the mandible. Curr Opin Otolaryngol Head Neck Surg. 2004 Dec. 12(6):513-8. [Medline].

39. González-García R, Naval-Gías L, Rodríguez-Campo FJ. Distraction osteogenesis in the irradiated mandible for segmental mandibular reconstruction. J Oral Maxillofac Surg. 2009 Jul. 67(7):1573-4. [Medline].

40. Grayson BH, McCormick S, Santiago PE, McCarthy JG. Vector of device placement and trajectory of mandibular distraction. J Craniofac Surg. 1997 Nov. 8(6):473-80; discussion 481-2. [Medline].

41. Guerrero CA, Bell WH, Gonzalez M. Intraoral distraction osteogenesis. Oral and Maxillofacial Surgery. Fonseca RJ, ed. Philadelphia: WB Saunders Co; 2000. Vol 2: 380-402.

42. Gugenheim JJ Jr. The Ilizarov method. Orthopedic and soft tissue applications. Clin Plast Surg. 1998 Oct. 25(4):567-78. [Medline].

43. Helman JI, Cottrell K, Garetz R. Outcome assessments in the surgical management of obstructive sleep apnea. Zurich, Switzerland: International Symposium on Problems and Complications in Corrective Surgery of Facial Skeletal Anomalies. University of Zurich; 2003.

44. Hollier LH Jr, Higuera S, Stal S, Taylor TD. Distraction rate and latency: factors in the outcome of pediatric mandibular distraction. Plast Reconstr Surg. 2006 Jun. 117(7):2333-6. [Medline].

45. Imola MJ. Craniofacial Distraction Osteogenesis. Medscape Reference Journal [serial online]. 2003. Available at: http://emedicine.medscape.com/article/844659-overview. [Full Text].

46. Janette AJ, Vicari FA, Baurer BS. Treatment of upper airway obstruction secondary to mandibular deficiency by distraction osteogenesis [abstract presentation]. American Association of Oral and Maxillofacial Surgeons. 1995.

47. Kunz C, Adolphs N, Buescher P, Hammer B, Rahn B. Distraction osteogenesis of the canine mandible: the impact of acute callus manipulation on vascularization and early bone formation. J Oral Maxillofac Surg. 2005 Jan. 63(1):93-102. [Medline].

48. Malkoç S, Iseri H, Karaman AI, Mutlu N, Küçükkolbasi H. Effects of mandibular symphyseal distraction osteogenesis on mandibular structures. Am J Orthod Dentofacial Orthop. 2006 Nov. 130(5):603-11. [Medline].

49. McCormick SU. Facial asymmetry. The diagnostic challenge. Atlas Oral Maxillofac Surg Clin North Am. 1996 Mar. 4(1):1-18. [Medline].

50. McCormick SU, Grayson BH, McCarthy JG, Staffenberg D. Effect of mandibular distraction on the temporomandibular joint: Part 2, Clinical study. J Craniofac Surg. 1995 Sep. 6(5):364-7. [Medline].

51. McKibbin B. The biology of fracture healing in long bones. J Bone Joint Surg. 1978. 60-B: 150-162.

52. Molina F, Ortiz Monasterio F. Mandibular elongation and remodeling by distraction: a farewell to major osteotomies. Plast Reconstr Surg. 1995 Sep. 96(4):825-40; discussion 841-2. [Medline].

53. Ortakoglu K, Karacay S, Sencimen M, Akin E, Ozyigit AH, Bengi O. Distraction osteogenesis in a severe mandibular deficiency. Head Face Med. 2007. 3:7. [Medline].

54. Ortiz Monasterio F, Molina F, Andrade L, Rodriguez C, Sainz Arregui J. Simultaneous mandibular and maxillary distraction in hemifacial microsomia in adults: avoiding occlusal disasters. Plast Reconstr Surg. 1997 Sep. 100(4):852-61. [Medline].

55. Paley D, Tetsworth K. Mechanical axis deviation of the lower limbs. Preoperative planning of uni-apical angular deformities of the tibia or femur. Clin Orthop Rel Res. 1992. 280: 48-64.

56. Paterson D. Leg-lengthening procedures. A historical review. Clin Orthop Relat Res. 1990 Jan. 27-33. [Medline].

57. Rachmiel A, Aizenbud D, Pillar G, Srouji S, Peled M. Bilateral mandibular distraction for patients with compromised airway analyzed by three-dimensional CT. Int J Oral Maxillofac Surg. 2005 Jan. 34(1):9-18. [Medline].

58. Rachmiel A, Jackson IT, Potparic Z, Laufer D. Midface advancement in sheep by gradual distraction: a 1-year follow-up study. J Oral Maxillofac Surg. 1995 May. 53(5):525-9. [Medline].

59. Sayan NB, Karasu HA, Uyank LO. Two-stage treatment of TMJ ankylosis by early surgical approach and distraction osteogenesis. J Craniofac Surg. 2007. 18(1):212-7.

60. Snyder CC, Levine GA, Swanson HM, Browne EZ Jr. Mandibular lengthening by gradual distraction. Preliminary report. Plast Reconstr Surg. 1973 May. 51(5):506-8. [Medline].

61. Stucki-McCormick SU, Fox RM, Mizrahi R. Distraction osteogenesis: a unique treatment for congenital micrognathias. Fonseca RJ, ed. Philadelphia: WB Saunders Co; 2000. 347-58.

62. Taylor TD, Stal S. Applications of distraction osteogenesis. Part I. Clin Plast Surg. 1998 Oct. 25(4):553-60, viii. [Medline].

63. Thompson SH, Quinn M, Helman JI. In press. Maxillomandibular distraction osteogenesis advancement for the treatment of OSA, a case report.

64. Tucker MR. Management of severe mandibular retrognathia in the adult patient using traditional orthognathic surgery. J Oral Maxillofac Surg. 2002 Nov. 60(11):1334-40. [Medline].

65. Waanders NA, Herzenberg JE, Goulet JA. A morphologic study of the regenerate bone structure in the early stages of distraction osteogenesis. Bull Hosp Joint Dis Orthop Inst. 1992. 52(1).

66. Walker DA. Management of severe mandibular retrognathia in the adult patient using distraction osteogenesis. J Oral Maxillofac Surg. 2002 Nov. 60(11):1341-6. [Medline].

67. Yasui N, Kojimoto H, Sasaki K, Kitada A, Shimizu H, Shimomura Y. Factors affecting callus distraction in limb lengthening. Clin Orthop Rel Res. 1993. 293: 55-60.

68. Yasui N, Kojimoto H, Shimizu H, Shimomura Y. The effect of distraction upon bone, muscle, and periosteum. Orthop Clin North Am. 1991 Oct. 22(4):563-7. [Medline].

69. Yonezawa H, Harada K, Ikebe T, Shinohara M, Enomoto S. Effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) on bone consolidation on distraction osteogenesis: a preliminary study in rabbit mandibles. J Craniomaxillofac Surg. 2006 Jul. 34(5):270-6. [Medline].

Dale A Baur, MD, DDS Vice Dean, Professor, and Chair, Department of Oral and Maxillofacial Surgery, Case Western Reserve University School of Dental Medicine; Division Chief, Oral and Maxillofacial Surgery, University Hospitals/Cleveland Medical Center

Dale A Baur, MD, DDS is a member of the following medical societies: American Association of Oral and Maxillofacial Surgeons, American College of Oral and Maxillofacial Surgeons, American Dental Association

Disclosure: consultant for: Checkpoint Surgical llc.

Joseph Helman, DMD C J Lyons Endowed Professor, Department of Oral and Maxillofacial Surgery, University of Michigan Medical School

Joseph Helman, DMD is a member of the following medical societies: American Association of Oral and Maxillofacial Surgeons, American Cleft Palate-Craniofacial Association, American Head and Neck Society, International Academy of Oral Oncology, American College of Oral and Maxillofacial Surgeons

Disclosure: Nothing to disclose.

Mehmet Ali Altay, DDS, PhD Research Fellow, Department of Oral and Maxillofacial Surgery, Case Western Reserve University School of Dental Medicine; Doctor of Oral and Maxillofacial Surgery, Faculty of Dentistry, Akdeniz University, Turkey

Mehmet Ali Altay, DDS, PhD is a member of the following medical societies: International Association of Oral and Maxillofacial Surgeons, Turkish Association of Oral and Maxillofacial Surgeons

Disclosure: Serve(d) as a director, officer, partner, employee, advisor, consultant or trustee for: Checkpoint Surgical LLC.

Juan Carlos Rodriguez, DDS Research Associate, Department of Oral and Maxillofacial Surgery, Case Western Reserve University School of Medicine

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Robert M Kellman, MD Professor and Chair, Department of Otolaryngology and Communication Sciences, State University of New York Upstate Medical University

Robert M Kellman, MD is a member of the following medical societies: American Academy of Facial Plastic and Reconstructive Surgery, American Head and Neck Society, American Rhinologic Society, Triological Society, American Neurotology Society, American Academy of Otolaryngology-Head and Neck Surgery, American College of Surgeons, American Medical Association, Medical Society of the State of New York

Disclosure: Nothing to disclose.

Arlen D Meyers, MD, MBA Professor of Otolaryngology, Dentistry, and Engineering, University of Colorado School of Medicine

Arlen D Meyers, MD, MBA is a member of the following medical societies: American Academy of Facial Plastic and Reconstructive Surgery, American Academy of Otolaryngology-Head and Neck Surgery, American Head and Neck Society

Disclosure: Serve(d) as a director, officer, partner, employee, advisor, consultant or trustee for: Cerescan;RxRevu;Cliexa;The Physicians Edge;Sync-n-Scale;mCharts<br/>Received income in an amount equal to or greater than $250 from: The Physicians Edge, Cliexa<br/> Received stock from RxRevu; Received ownership interest from Cerescan for consulting; .

Mimi S Kokoska, MD Physician, Department of Otolaryngology-Head and Neck Surgery, Aurora Health Care

Mimi S Kokoska, MD is a member of the following medical societies: American Academy of Facial Plastic and Reconstructive Surgery, American Academy of Otolaryngology-Head and Neck Surgery, American Association for Physician Leadership, American College of Surgeons, American Head and Neck Society

Disclosure: Nothing to disclose.

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