Labyrinthitis Ossificans Follow-up

1. Kaya S, Paparella MM, Cureoglu S. Pathologic Findings of the Cochlea in Labyrinthitis Ossificans Associated with the Round Window Membrane. Otolaryngol Head Neck Surg. 2016 Oct. 155 (4):635-40. [QxMD MEDLINE Link].

2. Trakimas DR, Knoll RM, Castillo-Bustamante M, Kozin ED, Remenschneider AK. Otopathologic Analysis of Patterns of Postmeningitis Labyrinthitis Ossificans. Otolaryngol Head Neck Surg. 2021 Jan. 164 (1):175-81. [QxMD MEDLINE Link].

3. Buch K, Baylosis B, Fujita A, et al. Etiology-Specific Mineralization Patterns in Patients with Labyrinthitis Ossificans. AJNR Am J Neuroradiol. 2019 Mar. 40 (3):551-7. [QxMD MEDLINE Link].

4. Bhatt S, Halpin C, Hsu W, et al. Hearing loss and pneumococcal meningitis: an animal model. Laryngoscope. 1991 Dec. 101(12 Pt 1):1285-92. [QxMD MEDLINE Link].

5. Paparella MM, Sugiura S. The pathology of suppurative labyrinthitis. Ann Otol Rhinol Laryngol. 1967 Aug. 76(3):554-86. [QxMD MEDLINE Link].

6. Brodie HA, Thompson TC, Vassilian L, et al. Induction of labyrinthitis ossificans after pneumococcal meningitis: an animal model. Otolaryngol Head Neck Surg. 1998 Jan. 118(1):15-21. [QxMD MEDLINE Link].

7. Nabili V, Brodie HA, Neverov NI, et al. Chronology of labyrinthitis ossificans induced by Streptococcus pneumoniae meningitis. Laryngoscope. 1999 Jun. 109(6):931-5. [QxMD MEDLINE Link].

8. Tinling SP, Colton J, Brodie HA. Location and timing of initial osteoid deposition in postmeningitic labyrinthitis ossificans determined by multiple fluorescent labels. Laryngoscope. 2004 Apr. 114(4):675-80. [QxMD MEDLINE Link].

9. Nadol JB Jr, Hsu WC. Histopathologic correlation of spiral ganglion cell count and new bone formation in the cochlea following meningogenic labyrinthitis and deafness. Ann Otol Rhinol Laryngol. 1991 Sep. 100(9 Pt 1):712-6. [QxMD MEDLINE Link].

10. Kaya S, Schachern PA, Tsuprun V, Paparella MM, Cureoglu S. Deterioration of Vestibular Cells in Labyrinthitis. Ann Otol Rhinol Laryngol. 2017 Feb. 126 (2):89-95. [QxMD MEDLINE Link].

11. Dodge PR, Davis H, Feigin RD, et al. Prospective evaluation of hearing impairment as a sequela of acute bacterial meningitis. N Engl J Med. 1984 Oct 4. 311(14):869-74. [QxMD MEDLINE Link].

12. Woolley AL, Kirk KA, Neumann AM, et al. Risk factors for hearing loss from meningitis in children: the Children's Hospital experience. Arch Otolaryngol Head Neck Surg. 1999 May. 125(5):509-14. [QxMD MEDLINE Link].

13. Kotzias SA, Linthicum FH Jr. Labyrinthine ossification: differences between two types of ectopic bone. Am J Otol. 1985 Nov. 6(6):490-4. [QxMD MEDLINE Link].

14. Novak MA, Fifer RC, Barkmeier JC, et al. Labyrinthine ossification after meningitis: its implications for cochlear implantation. Otolaryngol Head Neck Surg. 1990 Sep. 103(3):351-6. [QxMD MEDLINE Link].

15. Prades JM, Elmaleh-Berges M, Chatard S, Veyret C, Martin C, Richard C. [Computed tomography of the normal and pathologic temporal bone.]. Morphologie. 2011 Nov 10. [QxMD MEDLINE Link].

16. Booth TN, Roland P, Kutz JW Jr, Lee K, Isaacson B. High-resolution 3-D T2-weighted imaging in the diagnosis of labyrinthitis ossificans: emphasis on subtle cochlear involvement. Pediatr Radiol. 2013 Jul 11. [QxMD MEDLINE Link].

17. Arriaga MA, Carrier D. MRI and clinical decisions in cochlear implantation. Am J Otol. 1996 Jul. 17(4):547-53. [QxMD MEDLINE Link].

18. Jiang ZY, Odiase E, Isaacson B, Roland PS, Kutz JW Jr. Utility of MRIs in adult cochlear implant evaluations. Otol Neurotol. 2014 Oct. 35 (9):1533-5. [QxMD MEDLINE Link].

19. Lebel MH, Freij BJ, Syrogiannopoulos GA, et al. Dexamethasone therapy for bacterial meningitis. Results of two double- blind, placebo-controlled trials. N Engl J Med. 1988 Oct 13. 319(15):964-71. [QxMD MEDLINE Link].

20. Kadurugamuwa JL, Hengstler B, Zak O. Effects of antiinflammatory drugs of arachidonic acid metabolites and cerebrospinal fluid proteins during infectious pneumococcal meningitis in rabbits. Pediatr Infect Dis J. 1987. 6:1153-4.

21. Hartnick CJ, Kim HH, Chute PM, et al. Preventing labyrinthitis ossificans: the role of steroids. Arch Otolaryngol Head Neck Surg. 2001 Feb. 127(2):180-3. [QxMD MEDLINE Link].

22. Tuomanen E, Hengstler B, Rich R, et al. Nonsteroidal anti-inflammatory agents in the therapy for experimental pneumococcal meningitis. J Infect Dis. 1987 May. 155(5):985-90. [QxMD MEDLINE Link].

23. DeSautel MG, Brodie HA. Effects of depletion of complement in the development of labyrinthitis ossificans. Laryngoscope. 1999 Oct. 109(10):1674-8. [QxMD MEDLINE Link].

24. Yeung AH, Tinling SP, Brodie HA. Inhibition of post-meningitic cochlear injury with cerebrospinal fluid irrigation. Otolaryngol Head Neck Surg. 2006 Feb. 134(2):214-24. [QxMD MEDLINE Link].

25. Ge NN, Brodie SA, Tinling SP, et al. The effects of superoxide dismutase in gerbils with bacterial meningitis. Otolaryngol Head Neck Surg. 2004 Nov. 131(5):563-72. [QxMD MEDLINE Link].

26. Aminpour S, Tinling SP, Brodie HA. Role of tumor necrosis factor-alpha in sensorineural hearing loss after bacterial meningitis. Otol Neurotol. 2005 Jul. 26(4):602-9. [QxMD MEDLINE Link].

27. Liu CC, Sweeney M, Booth TN, et al. The Impact of Postmeningitic Labyrinthitis Ossificans on Speech Performance After Pediatric Cochlear Implantation. Otol Neurotol. 2015 Dec. 36 (10):1633-7. [QxMD MEDLINE Link].

28. Balkany T, Gantz B, Nadol JB Jr. Multichannel cochlear implants in partially ossified cochleas. Ann Otol Rhinol Laryngol Suppl. 1988 Sep-Oct. 135:3-7. [QxMD MEDLINE Link].

29. Gantz BJ, McCabe BF, Tyler RS. Use of multichannel cochlear implants in obstructed and obliterated cochleas. Otolaryngol Head Neck Surg. 1988 Jan. 98(1):72-81. [QxMD MEDLINE Link].

30. Lambert PR, Ruth RA, Hodges AV. Multichannel cochlear implant and electrically evoked auditory brainstem responses in a child with labyrinthitis ossificans. Laryngoscope. 1991 Jan. 101(1 Pt 1):14-9. [QxMD MEDLINE Link].

31. Steenerson RL, Gary LB. Multichannel cochlear implantation in obliterated cochleas using the Gantz procedure. Laryngoscope. 1994 Sep. 104(9):1071-3. [QxMD MEDLINE Link].

32. Rauch SD, Herrmann BS, Davis LA, et al. Nucleus 22 cochlear implantation results in postmeningitic deafness. Laryngoscope. 1997 Dec. 107(12 Pt 1):1606-9. [QxMD MEDLINE Link].

33. Brookhouser PE, Auslander MC, Meskan ME. The pattern and stability of postmeningitic hearing loss in children. Laryngoscope. 1988 Sep. 98(9):940-8. [QxMD MEDLINE Link].

34. Maxwell AK, Kahane JB, Mehta R, Arriaga MA. Cochlear implantation through intracochlear fibrosis: a comparison of surgical techniques. Cochlear Implants Int. 2023 Mar. 24 (2):73-82. [QxMD MEDLINE Link].

35. Hassepass F, Schild C, Aschendorff A, Laszig R, Maier W, Beck R, et al. Clinical outcome after cochlear implantation in patients with unilateral hearing loss due to labyrinthitis ossificans. Otol Neurotol. 2013 Sep. 34(7):1278-83. [QxMD MEDLINE Link].

Andrea H Yeung, MD Assistant Clinical Professor, Department of Otolaryngology-Head and Neck Surgery, University of California San Francisco

Andrea H Yeung, MD is a member of the following medical societies: Alpha Omega Alpha, Phi Beta Kappa

Disclosure: Nothing to disclose.

Hilary A Brodie, MD, PhD Professor and Chairman, Department of Otolaryngology-Head and Neck Surgery, University of California at Davis Medical Center

Hilary A Brodie, MD, PhD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Otolaryngology-Head and Neck Surgery, Association for Research in Otolaryngology, American Neurotology Society, American Medical Association, American Otological Society, Society of University Otolaryngologists-Head and Neck Surgeons

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Peter S Roland, MD Professor, Department of Neurological Surgery, Professor and Chairman, Department of Otolaryngology-Head and Neck Surgery, Director, Clinical Center for Auditory, Vestibular, and Facial Nerve Disorders, Chief of Pediatric Otology, University of Texas Southwestern Medical Center; Chief of Pediatric Otology, Children’s Medical Center of Dallas; President of Medical Staff, Parkland Memorial Hospital; Adjunct Professor of Communicative Disorders, School of Behavioral and Brain Sciences, Chief of Medical Service, Callier Center for Communicative Disorders, University of Texas School of Human Development

Peter S Roland, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Otolaryngic Allergy, American Academy of Otolaryngology-Head and Neck Surgery, American Auditory Society, American Neurotology Society, American Otological Society, North American Skull Base Society, Society of University Otolaryngologists-Head and Neck Surgeons, The Triological Society

Disclosure: Received honoraria from Alcon Labs for consulting; Received honoraria from Advanced Bionics for board membership; Received honoraria from Cochlear Corp for board membership; Received travel grants from Med El Corp for consulting.

Arlen D Meyers, MD, MBA Professor of Otolaryngology, Dentistry, and Engineering, University of Colorado School of Medicine

Arlen D Meyers, MD, MBA is a member of the following medical societies: American Academy of Facial Plastic and Reconstructive Surgery, American Academy of Otolaryngology-Head and Neck Surgery, American Head and Neck Society

Disclosure: Serve(d) as a director, officer, partner, employee, advisor, consultant or trustee for: Cerescan; Ryte; Neosoma; MI10<br/>Received income in an amount equal to or greater than $250 from: Neosoma; Cyberionix (CYBX)<br/>Received ownership interest from Cerescan for consulting for: Neosoma, MI10.

Jack A Shohet, MD President, Shohet Ear Associates Medical Group, Inc; Clinical Professor, Department of Otolaryngology-Head and Neck Surgery, University of California, Irvine, School of Medicine

Jack A Shohet, MD is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery, American Neurotology Society, California Medical Association

Disclosure: Medical Advisory Board Member, consultant for: Envoy Medical.

• Print this section
• Print the entire contents of
• Print the entire contents of article