Autoimmune Disease of the Inner Ear Medication

Updated: Sep 27, 2018
  • Author: Neeraj N Mathur, MBBS, MS, DNB(ENT), MNAMS, FAMS; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Medication

Medication Summary

The goals of pharmacotherapy are to prevent complications and reduce morbidity.

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Corticosteroids

Class Summary

These agents have anti-inflammatory properties and cause profound and varied metabolic effects. Corticosteroids modify the body's immune response to diverse stimuli.

Prednisone (Sterapred)

Immunosuppressant for treatment of autoimmune disorders; may decrease inflammation by reversing increased capillary permeability and suppressing PMN activity.

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Cytotoxic agents

Class Summary

These agents inhibit cell growth and proliferation and are useful in the treatment of autoimmune diseases.

Cyclophosphamide (Cytoxan, Neosar)

Chemically related to nitrogen mustards. An alkylating agent; mechanism of action of active metabolites may involve cross-linking of DNA, which may interfere with growth of normal and neoplastic cells.

Methotrexate (Folex PFS, Rheumatrex)

Unknown mechanism of action in treatment of inflammatory reactions; may affect immune function. Ameliorates symptoms of inflammation (eg, pain, swelling, stiffness).

Adjust dose gradually to attain satisfactory response.

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