Infectious or Allergic Chronic Laryngitis Medication

Updated: Apr 17, 2019
  • Author: Stefano Berliti, MD, FACP; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Medication Summary

S aureus is a frequent causative organism in cases of chronic bacterial laryngitis. Antimicrobial therapy should cover gram-positive and gram-negative pathogens.



Class Summary

Initial empiric antimicrobial therapy must be comprehensive and should cover both aerobic and anaerobic gram-negative organisms.

Amoxicillin and clavulanate (Augmentin)

Provides broad coverage for gram-positive, gram-negative, and anaerobic bacteria. Peak serum levels are higher than those of ampicillin. Drug combination treats bacteria resistant to beta-lactam antibiotics. Children > 3 mo, dose based on amoxicillin content. Because of different amoxicillin/clavulanic acid ratios in 250-mg tab (250/125) vs 250-mg chewable tab (250/62.5), do not use 250-mg tab until child weighs >40 kg.