Snapping Hip Syndrome Medication

Updated: Aug 30, 2017
  • Author: Joseph P Garry, MD, FACSM, FAAFP; Chief Editor: Craig C Young, MD  more...
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Medication Summary

NSAIDs are the drugs of choice for treating pain associated with snapping hip syndrome. This class of drugs provides good analgesia and possible anti-inflammatory effects for concomitant conditions.


Nonsteroidal anti-inflammatory drugs

Class Summary

These drugs have analgesic, anti-inflammatory, and antipyretic activities. Mechanism of action is not known, but NSAIDs may inhibit cyclooxygenase (COX) activity and prostaglandin synthesis. Other mechanisms may coexist, such as inhibition of leukotriene synthesis, lysosomal enzyme release, lipoxygenase activity, neutrophil aggregation, and various cell-membrane functions.

Ibuprofen (Ibuprin, Advil, Motrin)

DOC for mild to moderate pain. Inhibits inflammatory reactions and pain by decreasing prostaglandin synthesis.

Naproxen (Anaprox, Naprelan, Naprosyn)

For relief of mild to moderate pain; inhibits inflammatory reactions and pain by decreasing activity of COX, which is responsible for prostaglandin synthesis. May demonstrate more analgesia compared to ibuprofen.


Cyclooxygenase-2 inhibitors

Class Summary

Although increased cost can be a negative factor, the incidence of expensive and potentially fatal GI bleeds is clearly less with COX-2 inhibitors than with traditional NSAIDs. Ongoing analysis of cost avoidance of GI bleeds will further define populations that will benefit most from COX-2 inhibitors.

Celecoxib (Celebrex)

Inhibits primarily COX-2. COX-2 is considered an inducible isoenzyme, induced during pain and inflammatory stimuli. Inhibition of COX-1 may contribute to NSAID GI toxicity. At therapeutic concentrations, COX-1 isoenzyme is not inhibited, thus GI toxicity may be decreased. Seek lowest dose for patient.


Analgesic agents

Class Summary

Simple analgesics may be preferred for conditions in which NSAIDs are not advised or for which an underlying inflammatory process is doubtful.

Acetaminophen (Tylenol, Panadol, Aspirin-Free Anacin)

DOC for pain in patients with documented hypersensitivity to aspirin or NSAIDs or those diagnosed with upper GI disease or on oral anticoagulants.