B-Cell and T-Cell Combined Disorders Questions & Answers

Updated: Aug 08, 2019
  • Author: Terry W Chin, MD, PhD; Chief Editor: Harumi Jyonouchi, MD  more...
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Questions & Answers

Overview

What are combined B-cell and T-cell disorders?

What is the pathophysiology of combined B-cell and T-cell disorders?

What is the role of genetics in the pathophysiology of combined B-cell and T-cell disorders?

What is the role of the immune and endocrine systems in the pathophysiology of combined B-cell and T-cell disorders?

What is the prevalence of ataxia-telangiectasia (AT)?

What is the prevalence of Nijmegen breakage syndrome?

What is the mortality and morbidity associated with combined B-cell and T-cell disorders?

What are the racial predilections of combined B-cell and T-cell disorders?

What are the sexual predilections of combined B-cell and T-cell disorders?

At what age are combined B-cell and T-cell disorders typically diagnosed?

What is the prognosis of combined B-cell and T-cell disorders?

What is included in patient education about combined B-cell and T-cell disorders?

Presentation

Which clinical history findings are characteristic of combined B-cell and T-cell disorders?

Which physical findings are characteristic of combined B-cell and T-cell disorders?

What causes combined B-cell and T-cell disorders?

DDX

What are the differential diagnoses for B-Cell and T-Cell Combined Disorders?

Workup

What is the role of lab tests in the workup of combined B-cell and T-cell disorders?

What is the role of imaging studies in the workup of combined B-cell and T-cell disorders?

What is the role of EMG in the workup of combined B-cell and T-cell disorders?

What is the role of cytogenetics in the workup of combined B-cell and T-cell disorders?

What is the role of immunoelectrophoresis in the workup of combined B-cell and T-cell disorders?

What is the role of antibody testing in the workup of combined B-cell and T-cell disorders?

Which histologic findings are characteristic of combined B-cell and T-cell disorders?

How are combined B-cell and T-cell disorder-related lymphomas staged?

Treatment

How are combined B-cell and T-cell disorders treated?

Which specialist consultations are beneficial to patients with combined B-cell and T-cell disorders?

Which dietary modifications are used in the treatment of combined B-cell and T-cell disorders?

Which activity modifications are used in the treatment of combined B-cell and T-cell disorders?

Medications

What is the role of medications in the treatment of combined B-cell and T-cell disorders?

What is the role of IVIG in the treatment of combined B-cell and T-cell disorders?

Which medications in the drug class Anti-infective Agents are used in the treatment of B-Cell and T-Cell Combined Disorders?

Which medications in the drug class Antibodies are used in the treatment of B-Cell and T-Cell Combined Disorders?