Pediatric Complement Receptor Deficiency Medication

Updated: Aug 06, 2019
  • Author: Alan P Knutsen, MD; Chief Editor: Harumi Jyonouchi, MD  more...
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Medication Summary

Patients with leukocyte adhesion deficiency (LAD) type 1 are susceptible to various bacterial infections. To direct appropriate antibiotic therapy, obtaining cultures from infectious sites is essential. Infections with Staphylococcus, Pseudomonas, Klebsiella, and Enterococcus species and E coli are common. Therefore, antibiotic coverage of these organisms may be initiated until the specific organism is identified and sensitivity is completed.

Although some patients have been treated with prophylactic antibiotics, their use in LAD has not been demonstrated. Immunizations should be continued in these patients because antibody responses are present although abnormal.