Myeloperoxidase Deficiency Treatment & Management

Updated: Nov 10, 2021
  • Author: Maureen M Petersen, MD; Chief Editor: Harumi Jyonouchi, MD  more...
  • Print

Medical Care

In general, routine treatment with prophylactic antibiotics is not recommended because most patients with myeloperoxidase (MPO) deficiency have no increased incidence of infections.

  • Exercise caution in patients with concomitant diabetes mellitus. If infection does occur, initiate prompt and aggressive treatment with antimicrobials. Every effort should be made to identify causative agents and administer specific antimicrobial therapy.

  • If possible, avoid any treatments that might increase the likelihood of developing fungal infection (eg, use of broad-spectrum antibiotics, prolonged courses of antibiotics).