T-Cell Disorders Questions & Answers

Updated: Jun 12, 2020
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Harumi Jyonouchi, MD  more...
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Questions & Answers

Overview

What are T-cell disorders?

What is the pathophysiology of T-cell disorders?

What is the prevalence of T-cell disorders in the US?

What is the global prevalence of T-cell disorders?

What is the mortality and morbidity associated with T-cell disorders?

What are the racial predilections of T-cell disorders?

What are the sexual predilections of T-cell disorders?

Which T-cell disorders are associated with autosomal chromosomes?

At what age do T-cell disorders typically present?

Presentation

Which clinical history findings are characteristic of T-cell disorders?

Which physical findings are characteristic of T-cell disorders?

What causes T-cell disorders?

What does a finding of cutaneous granulomas indicate in the physical exam for T-cell disorders?

DDX

Which genetic disorders are associated with T-cell disorders?

What are the differential diagnoses for T-Cell Disorders?

Workup

What is the role of lab tests in the workup of T-cell disorders?

What is the role of imaging studies in the workup of T-cell disorders?

What is the role of mutational analysis in the workup of T-cell disorders?

What is the role of cytotoxicity analysis in the workup of T-cell disorders?

What is the role of biopsy in the workup of T-cell disorders?

Which histologic findings are characteristic of T-cell disorders?

Treatment

How are T-cell disorders treated?

What is the role of surgery in the treatment of T-cell disorders?

Which specialist consultations are beneficial to patients with T-cell disorders?

Which dietary modifications are used in the treatment of T-cell disorders?

Which activity modifications are used in the treatment of T-cell disorders?

Medications

What is the role of medications in the treatment of T-cell disorders?

What is the role of IV immunoglobulin replacement in the treatment of T-cell disorders?

Which medications in the drug class Tumor Necrosis Factor Inhibitors are used in the treatment of T-Cell Disorders?

Which medications in the drug class Vaccines are used in the treatment of T-Cell Disorders?

Which medications in the drug class Immunosuppressive Agents are used in the treatment of T-Cell Disorders?

Which medications in the drug class Respiratory Syncytial Virus Antibodies are used in the treatment of T-Cell Disorders?

Follow-up

How are common infections treated in patients with T-cell disorders?

How are eczematous rashes treated in patients with T-cell disorders?

How is neurologic dysfunction treated in T-cell disorders?

When is inpatient care indicated for the treatment of T-cell disorders?

When is patient transfer indicated for the treatment of T-cell disorders?

What is the role of mutational analysis in the prevention of T-cell disorders?

How are T-cell disorders prevented?

What are the possible complications of T-cell disorders?

What is the prognosis of T-cell disorders?

What is included in patient education about T-cell disorders?